A vaccine against cat allergies: the latest news

[ad_1]

<div _ngcontent-c15 = "" innerhtml = "

Hey, cats. Do you know that about 10% of humans in the United States start coughing, wheezing, sneezing and having rashes and stuffy noses around you? Well, it is not them. That's you. They are & nbsp; allergic to you.

This problem motivated HypoPet AG, a company based in Switzerland, to develop & nbsp;the& nbsp; HypoCat vaccine for that. But the vaccine is not for them. This is for you.

Most often, the problem is not quite you. It's actually & nbsp;Fel d 1. No, Fel d 1 is not something on World of Warcraft. It would be a bottle of Fel Mint Green paint. And this is not a musical act. It would be Adele or Bell Biv DeVoe. & Nbsp; Fel d 1 & is a protein of saliva and skin secretions that frequently generates an allergic reaction in humans.

What aggravates the problem is that you have licked this problem. Maybe it's lack of hair gel and a brush, but you seem to lick yourself quite often. This licking then spreads Fel d 1 on your fur. Then, when you lose your fur, you effectively spread this protein wherever you go. This is what can make the presence of certain human beings around you so difficult. & Nbsp;

I know, I know, you may not want people around you. After all, they can dress you like a sailor or watch you while you pee. But many humans like to be around you, even if you are considering their disappearance.

That's why humans are trying to develop a vaccine against cat allergies. Have you read that published in the latest issue of & nbsp;Journal of Allergy and Clinical Immunology?& nbsp;& nbsp; No, not the one on the & nbsp;Safety and long-term pharmacodynamics of mepolizumab in severe asthmatic children with eosinophilic phenotype. I know how much you love pharmacodynamics. I am referring instead to the publication of a series of studies involving more than fifty of your classmates (or cats), mice, human blood and the HypoCat vaccine.

During the studies, your catrades received three doses of HypoCat over a nine-week period and some received a booster injection six months later. Vaccinations involved injections in & nbsp; your later catrades. Some injections may have involved meowing but were tolerated well enough. No strange side effects No Cat Daddy Dances.

After administering the vaccines, the researchers subsequently detected an increase in the levels of anti-Fel d 1 antibodies in the blood of your catrades. They (the researchers and not the cats) also found that these antibodies seemed to neutralize the activity of Fel d 1 when they were mixed in the laboratory. In addition, catrades that received the vaccine tended to have lower levels of Fel d 1 in their saliva and tears. Finally, when the samples of your cats that received the vaccine were mixed with human blood with allergies, there was less allergy-related chemical reactions than usual.

Gary Jennings, CEO of HypoPet AG, said in a statement:"We are very pleased to release this data which shows that our HypoCat vaccine is capable of producing high levels of antibodies in cats and that these antibodies can bind and neutralize the allergen Fel d 1 produced by animals. . " continue registration studies and discussions with European and American regulators in the hope of marketing this indispensable product. "

To my knowledge, Jennings is a human and not a cat.

Of course, these latest studies do not fully prove that humans will not continue to sneeze, cough, breathe, and not develop rashes around you if you get vaccinated. We will have to see what will happen when humans with documented cat allergies will be exposed to your catrades who have received the vaccine. But these results are promising.

If you are worried about what the neutralization of your Fel d 1 can do to you, you do not know why Fel d 1 can serve you. The hope is that & nbsp; Fel d 1 looks like a bad body odor or Macarena. It exists. This disturbs a number of humans. But you do not mind getting rid of it. Unless, of course, you think that & nbsp; cat allergies & nbsp; keep humans from getting dressed as a sailor & Nbsp; & nbsp;

">

Hey, cats. Do you know that about 10% of humans in the United States start coughing, wheezing, sneezing and having rashes and stuffy noses around you? Well, it is not them. That's you. They are allergic to you.

This problem motivated HypoPet AG, a company based in Switzerland, to develop the HypoCat vaccine for that. But the vaccine is not for them. This is for you.

Most often, the problem is not quite you. It's actually Fel d 1. No, Fel d 1 is not something on World of Warcraft. It would be a bottle of Fel Mint Green paint. And this is not a musical act. It would be Adele or Bell Biv DeVoe. Fel d 1 is a protein of saliva and skin secretions that frequently generates an allergic reaction in humans.

What aggravates the problem is that you have licked this problem. Maybe it's lack of hair gel and a brush, but you seem to lick yourself quite often. This licking then spreads Fel d 1 on your fur. Then, when you lose your fur, you effectively spread this protein wherever you go. This is what can make the presence of men around you so difficult.

I know, I know, you may not want people around you. After all, they can dress you like a sailor or watch you while you pee. But many humans like to be around you, even if you are considering their disappearance.

That's why humans are trying to develop a vaccine against cat allergies. Have you read this publication in the last issue of Journal of Allergy and Clinical Immunology? No, not the one on the long-term safety and pharmacodynamics of mepolizumab in severely asthmatic children with eosinophilic phenotype. I know how much you love pharmacodynamics. I am referring instead to the publication of a series of studies involving more than fifty of your classmates (or cats), mice, human blood and the HypoCat vaccine.

During the studies, your catrades received three doses of HypoCat over a nine-week period and some received a booster injection six months later. Vaccinations involved injections into the back legs of your cat. Some injections may have involved meowing but were tolerated well enough. No strange side effects No Cat Daddy Dances.

After administering the vaccines, the researchers subsequently detected an increase in the levels of anti-Fel d 1 antibodies in the blood of your catrades. They (the researchers and not the cats) also found that these antibodies seemed to neutralize the activity of Fel d 1 when they were mixed in the laboratory. In addition, catrades that received the vaccine tended to have lower levels of Fel d 1 in their saliva and tears. Finally, when the samples of your cats that received the vaccine were mixed with human blood with allergies, there was less allergy-related chemical reactions than usual.

Gary Jennings, CEO of HypoPet AG, said in a statement: "We are very pleased to release this data which shows that our HypoCat vaccine is capable of producing high levels of antibodies in the cat and that these antibodies can bind and neutralize the allergen produced by the animals. "We are pursuing registration studies and discussions with European and American regulators in the hope of marketing this indispensable product."

To my knowledge, Jennings is a human and not a cat.

Of course, these latest studies do not fully prove that humans will not continue to sneeze, cough, breathe, and not develop rashes around you if you get vaccinated. We will have to see what will happen when humans with documented cat allergies will be exposed to your catrades who have received the vaccine. But these results are promising.

If you are worried about what the neutralization of your Fel d 1 can do to you, you do not know why Fel d 1 can serve you. The hope is that Fel d 1 looks like a bad body odor or Macarena. It exists. This disturbs a number of humans. But you do not mind getting rid of it. Unless, of course, you think that cat allergies prevent humans from getting dressed as a sailor.