A successful diet slows hair loss and the appearance of gray hair

A successful experiment on mice by the Johns Hopkins University School of Medicine and concluded that a compound slows down the fall of hair and graying, according to a study published Monday by Scientific Reports. According to research, a mixture would slow down the production of certain fats called glycosphingolipids (GSL), which are found in the skin and other cell membranes.

The compound D-PDMP (made with D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol) showed its effectiveness after the experiment carried out with two groups of mice : one based on a Western diet high in fat and cholesterol and a second group with a standard diet.

Researchers say the compound stops the production of certain fats called glycosphingolipids, or GSL, which are major components of the skin and other cell membranes. The work shows that mice fed a diet high in fat and cholesterol are more likely to have discoloration of hair from black to gray and white, significant hair loss and inflammation of the skin. Feeding these animals with the compound, however, seems to reverse these symptoms.

The findings of the research were extracted after feeding, from 12 to 20 weeks, a group of mice with a Western diet rich in fats and cholesterol, and a second group with a standard diet [19659010]. Compared with those who received standard food, mice with western nutrition lost and suffered graying hair as well as skin lesions.

These results became more severe when mice continued to eat a Western diet for 36 weeks, with 75% of rodents having hair problems and multiple skin lesions. "Our results show that a Western diet causes hair loss and graying and inflammation of skin in mice. We believe that humans who consume a diet high in fats and cholesterol live a similar process, "said Dr. Subroto Chatterjee, professor of pediatric medicine at Johns Hopkins University.

According to the article in Scientific Reports, such results mice do not mean that the same effects would occur in people, and there is no evidence at the moment that the compounds they use are safe for people, but the results, they add, illuminate possible pathways to treat hair loss and skin lesions in humans by oral or topical medications.

Chatterjee pointed out that "more research is needed, but our results are promising one day a drug for skin diseases such as psoriasis and injuries resulting from diabetes or plastic surgery ". The professor of medicine said: "We hope that someday in the future this could mean faster and more effective recovery from baldness, graying hair in aging populations and wound healing."