[ad_1]
The scientists observed that, although in the case of the patients hospitalized production antibody is superior, its ability to block new coronavirus variants is more affected than patients asymptomatic or with mild symptoms, which generate fewer antibodies, but more protective against new variants of the virus.
The vaccination caused their antibody levels to increase in all individuals in the study, reaching very similar amounts in all.
For the preparation of the study, they participated 332 people who spent the covid-19, both in a way asymptomatic and mild, about 60%, as serious, the remaining 40%, and their neutralizing immune response was monitored for 15 months.
So the researchers confirmed that in most cases, antibody levels are maintained for more than a year, providing protection against covid-19.
“What we have seen throughout this year is that in hospitalized patients, the protective antibodies reach their maximum level a few days after showing the first symptoms and then decrease sharply, until stabilizing, remaining high in time “, explains Edwards Pradenas, undergraduate researcher. to IrsiCaixa and one of the study authors.
“In the case of people who have spent a covid-19 In an asymptomatic or mild manner, the levels of protective antibodies, although they are also maintained over time, remain lower, ”he adds.
Scientific staff have determined that in the case of hospitalized patients, the quality of the antibodies is poorer.
In fact, the study shows that the protective capacity of antibodies against the beta variant, which first appeared in South Africa, is lost more markedly in hospitalized patients than in people who have passed COVID-19. asymptomatically or mildly.
“Recent data suggests that in the absence of a vaccine, 50% of study participants could experience reinfection with the beta variant of the virus, the most resistant to antibodies described so far, and this percentage would drop to 30. % in the case of the original virus, ”comments Julià Blanco, IrsiCaixa researcher.
The administration of the vaccine allowed the antibody levels of the people participating in the study, of different amplitude according to the symptoms, to reach comparable values.
“Although not all of the people we followed received the full immunization schedule, we can say that in all of them their immune response against the virus was enhanced, demonstrating, once again, the clear benefits of the vaccine. vaccination “, famous Bonaventura. Clotet, director of IrsiCaixa.
Eph.
.
[ad_2]
Source link