the frequency of detection of Manau and Andina variants increased in AMBA

The Gamma variant (P.1, Manaus) reached frequencies above 35% in CABA and 27% in Greater Buenos Aires (GBA), and the C.37 (Andina) line had frequencies above 42% in CABA and 32% in GBA.

As for the Alpha variant of the coronavirus (B.1.1.7, United Kingdom), its frequency decreased to less than 10% in CABA and 15% in GBA.

Likewise, during this period, less than 6% (CABA) and 5% (GBA) of the cases analyzed belonged to the other variants or presented mutations of interest.

In total, over 95% of SARS-CoV-2 that circulated in AMBA have mutations in the region that codes for the Spike protein that differentiates it from viruses that circulated in the first wave.

Meanwhile, the Alpha variant (B.1.1.7, UK) has been identified in 45 cases, of which nine correspond to CABA, 16 to GBA (four from GBA North and 12 from GBA West), four within PBA and two cases of AMBA with no definite origin.

In addition, nine cases corresponded to the province of Entre Ríos, one case to the province of Neuquén and four to the province of Santa Fe.

With the exception of the case of Neuquén, the cases correspond to individuals without a history of travel abroad or close contact with travelers.

Meanwhile, the Gamma variant (P.1, Manaus) was recorded in 181 cases: 51 were from CABA, 52 GBA cases (nine from GBA North, 17 from GBA West and 26 from GBA South) and 12 from inside the PBA.

In addition, 13 cases corresponded to the province of Entre Ríos, 24 cases to the province of Neuquén, 14 cases to the province of Santa Fe and 13 cases to the province of Córdoba.

All of these cases correspond to infections of individuals without a history of travel abroad or close contact with travelers.

In turn, they added that in the province of Cordoba, two cases have been detected in people with a history of travel to Paraguay and Brazil.

The combination of mutations compatible with the C.37 or “Andean variant” line was identified in a total of 127 cases.

About 50 cases are from CABA, 56 cases from GBA (five from GBA North, 19 from GBA West and 32 from GBA South), four from inside PBA.

Two cases corresponded to the province of Entre Ríos, six cases to the province of Neuquén and seven cases to the province of Córdoba.

All these cases correspond to infections of individuals without a history of travel abroad or of close contact with travelers, with the exception of two cases from the province of Cordoba which presented with a history of travel to Mexico and the Republic. Dominican.

So far, out of a total of 2,238 samples analyzed by active surveillance by Spike or whole genome sequencing, the most detected variants were the C.37 line (Andean variant) in 412 cases and the Gamma variant (P. 1, Manaus) in 398 cases, notably in the last SE analyzed.

The PAIS project estimated that the C.37 line (Andean variant) should “be considered at least as a variant of regional interest, given the sustained increase in its frequency of detection in the AMBA region in recent weeks. epidemiological, as has also been observed in countries in the region such as Peru and Chile ”.