The study with viagra is canceled after the death of 11 babies

The Medical Center of the University of Amsterdam stopped an investigation with immediate effect after eleven newborns were dead from an illness pulmonary . This was an investigation into a drug for pregnant women whose child has extreme growth retardation. The children already had a bad prognosis.

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The hope was that the vasodilator sildenafil better known as the name viagra promoted the blood flow of the placenta and therefore the growth of the baby.

 

  
  

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The study involved 183 pregnant women and a total of ten hospitals . The UMC Amsterdam, in which AMC and the VU hospital were merged, was in charge, where 90 women received viagra 93 women a false pill. Eleven babies died in the Viagra group, nine in the placebo group.

Pulmonary disease was fatal in eleven cases in the viagra group. Another group of eight babies died in the group where sildenafil was taken, but died from other causes. Deaths in the control group had other causes.

 

  
  

The study included only women who were pregnant with a baby with severe growth deficiency very early, between 20 and 30 weeks.

There is still no medicine for such cases. Extremely light babies are often born (too much) prematurely. Low weight and premature birth are very risky.

These are not badly torn alveoli, as is usually seen in premature babies, but a kind of arterial hypertension in the lungs. As a result, babies receive very little oxygen. The research, which began in 2015, will continue until 2020. 350 patients will participate.