They find out how to avoid cases of thrombosis after applying certain coronavirus vaccines

After global controversy due to isolated cases of thrombosis in some people who had been vaccinated against covid with Astrazeneca and Johnson & Johnson, a group of Austrian researchers discovered a cocktail medicines which, if administered quickly, can save the life patients who experience this side effect after inoculation.

Specialists from the Department of Medicine at the University of Vienna and the General Hospital in the Austrian capital have revealed that the combination of anti coagulants (without heparin), immunoglobulins in high doses and cortisone is very effective in avoiding severe thrombosis.

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Although these are situations very strange, the few cases of thrombosis associated with the application of these two vaccines generated Doubts all over the world, to the point that some countries such as Denmark they forbade the application of Astrazeneca in their population, while Germany and France have limited it to people over 60 years of age.

According to specialists in the scientific studies, published in the magazine Journal of Thrombosis and Hemostasis, this drug cocktail can reverse the call VIPIT (vaccine-induced prothrombotic thrombocytopenia syndrome). It appears on rare occasions after application of the covid vaccine, it is very rare, but it can be mortal if it is not processed on time.

It is a condition very similar to a rare side effect of heparin (an anticoagulant) called Heparin-induced thrombocytopenia (HIT). What happens in these cases is that a component of the vaccine binds to a protein called plaquetario factor 4 (PF4) and form a complex. Some people generate antibody against this complex, which causes a low level of platelets and a increases thrombin (a protein that promotes the formation of clots or thrombi), which can trigger an “uncontrolled clotting reaction” and promote blood clotting. thrombosis. “It’s a exaggerated immune response Yes unnatural to the vaccine, which is very rare, ”the researchers stressed.

The specialists further explained that the immunoglobulins contain antibodies that can block an incorrect immune response, but make it clear that anti coagulants that are administered cannot be heparin because in these cases, they could trigger a thrombosis.

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“Our case (a 62-year-old woman who had received AstraZeneca and nine days later, he started with symptoms of thrombosis) is the first to suggest that the early administration of anticoagulants heparin free (the strange reaction to the vaccine is similar to a rare effect of heparin) and the high doses of immunoglobulins can stop the thrombotic process in patients with VIPIT and save their lives. This experience could be of great help in the treatment of other patients “, the hematologist pointed out Paul Knöbl, coordinator of the scientific study.

The Spanish Federation of Medical and Scientific Associations recommends the treatment of VIPIT the following: “Manage intravenous immunoglobulin; avoid using heparin, using as anticoagulant argatroban, bivalirudin, fondaparinux, rivaroxaban or apixaban, and avoid platelet transfusions ”.

The rate of VIPIT Mortality it is high (40%) and requires immediate treatment. However, more scientific evidence is still lacking in this regard.