World Lupus Day: How is the fight against the disease

May 10, 2019

90% of cases of this disease are women between 20 and 40 years old. Currently, there are more than 40 different treatments to control it.

The Lupus is a chronic autoimmune disease in which the immune system becomes unbalanced and produces antibodies that attack healthy tissues and organs. Disease It most often affects the skin, joints, kidneys, brain, heart and lungs.

Currently, There are about 40 different treatments in the clinical development phase. Recently, it has been discovered that people with lupus have lower-than-normal "messengers" of RNA (ribonucleic acid). According to Chinese scientists, an immune response against the virus is thus triggered.

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The biochemist Lingling Chen, of the Institute of Biochemistry and Cell Biology of Shanghai, has studied the fact that activating the fight mechanisms without harmful viruses can cause the immune system to attack the body.

"This raises an intriguing possibility that the introduction of some messenger RNAs may reduce the autoimmunity badociated with lupus, suggesting a new therapeutic strategy," said Howard Chang, a geneticist at Stanford University. .

In the same vein, Amanda Ríos (MN 59758), a dermatologist at San Juan de Dios Hospital and specialist in collagen diseases, said: "Currently, in the treatment of lupus, immunosuppressants are used"And he said it starts" with corticosteroids, to cut off the mechanism of action of immunity that acts against our own cells. "Early diagnosis and early treatment can help control their impact ", he added.

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The environmental factor that is most related to the disease is ultraviolet radiation. This causes an exacerbation in 70% of patients. For this reason, it is always recommended to protect yourself from the sun and get vaccinated against the flu.

"Up to 90% of cases are women of childbearing age. But there is a predisposition in both bades, at all ages and in all ethnic groups, "Ríos said.

In addition, he said that they are studying that treatments are more targeted. "Early diagnosis and early treatment can help control its impact," he concluded.