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- It should be noted that this randomized trial found that energy-restricted intermittent regimes were not inferior to energy-restricted continuous diets in terms of variation in energy intensity. A1C hemoglobin in diabetic patients
- Diabetes may result in an increased risk of hypoglycemia if the drugs are not properly adjusted.
Intermittent intermittent fasting, with daily caloric intake less than 600 kcal for 2 days a week, resulted in a similar reduction in blood glucose compared to an as did a non-inferiority trial, people with type 2 diabetes who were following a restricted intermittent diet for 2 days a week saw reductions in average HbA1c levels similar to those who followed a continuous diet. diet restricted in energy (-0.5% [continuous] against -0.3% [intermittent] P = 0.65, difference between groups 0.2%, CI 90% -0.2 % to 0.5%), Shar ayah Carter, BND, from the University of South Australia in Adelaide, and colleagues reported in JAMA Network Open .
Although both diets also have similar amounts of weight loss – 11 lb weight (5.0 kg) loss for steady-state versus 15 lb (6.8 kg) loss for intermittent diet ( P = 0.25) – these results did not show statistical equivalence, since the average difference between the groups was greater than the precpecified
Similar results were reported for fat loss and fat-free mbad loss for diets, as well. Although the mean reductions were generally similar between the two types of diets, the differences between the groups decreased slightly from the predefined equivalence limit, favoring the intermittent restriction group as follows:
- Total body fat : -7.5 lbs (95% CI -10.1 to -4.9) [continuous] vs. -10.4 lbs (95% CI -13.4 to -7.5) ( P = 0.20) [intermittent]
- Fat free mbad: -3.5 lbs (95% CI: -5.1 to -1.8) vs. -4.6 lbs (95% CI: -6.4 to -3.1) ( P = 0.11)
Participants in both diets saw their weight loss continue for up to 12 months. While the total weight loss recorded after 12 months was badociated with the person's weight change after 2 weeks of dieting, a small number of people in both groups continued to lose weight throughout the year. (Average weight loss: 18.5 lb (8.4 kg) [continuous] vs. 27.6 lb (12.5 kg) [intermittent] P = 0.07).
Similarly, those who follow both diets also have similar results for other clinical markers after 12 months – improvement in lipid levels, total score of the drug effect, fasting glucose, and number total of steps.
Both groups also had a similar number of hypoglycemic and hyperglycemic events during the first two weeks of their diet (mean number of events: 3.2 [continuous] vs. 4.9 [intermittent] P = 0.28).
The badysis involved a total of 97 adults with type 2 diabetes who completed the 12-month trial. The average body mbad index at inclusion was 36.0 and the average age was 61 years old; Participants were randomized to follow either a restricted intermittent diet – involving limiting their diet to 500-600 kcal per day for 2 days of the week, consisting of at least 50 grams of protein and their usual diet. other days – or a continually restricted diet consisting of 1,200-1,500 kcal / d followed daily, with 30% protein, 45% carbs and 25% fat.
To further illustrate a real-world experience, no meal replacement or food was provided to participants.
"For the record, participants in the intermittent energy restriction group stated that even though they did not follow the protocol routinely after 3 months, they found that they could not follow the protocol routinely after 3 months, they found that use effectively to prevent weight gain because the energy restriction only took two days. "
Although intermittent fasting is safe and does not cause hypoglycemia in people who are on a diet or medication. To control their type 2 diabetes, the Carter group also suggests that for sulfonylureas or Insulin, "intermittent energy restriction requires medication changes and regular monitoring, especially at the initial stages." These people should consult their health care professional before starting.
"In our trial, hypoglycemic events occurred only in participants who reported having had hypoglycaemia before starting treatment or who were uncertain, "the team adds.
With respect to future research in this area, the authors suggest that participants should use continuous blood glucose monitoring systems to obtain more accurate results for
Carter was supported by a postgraduate award from the University of South Australia and another co-author was supported by a National Council of Medical and Medical Research.
Carter and his coauthors declared to have no conflict of interest
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Reviewed by
F. Perry Wilson, MD, MSCE Assistant Professor, Nephrology Section, Yale School of Medicine and Dorothy Caputo, MA, BSN, RN, Nurse Planner
1969-12-31T19: 00: 00-0500
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