Aging: Farewell to wrinkles and baldness: Now you may be able to reverse the signs of aging



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NEW YORK: Scientists, including an Indian descent, have found a way to reverse the action of wrinkled skin and hair loss that are considered aging features , in a mouse model.

The results showed that when a mutation leading to mitochondrial dysfunction is induced, the mouse develops wrinkled skin and significant and visible hair loss within a few weeks.

However, when mitochondrial function is restored by extinguishing the gene responsible for its dysfunction, the mouse returns to the smooth skin and thick fur, indistinguishable from a healthy mouse of the same age.

According to the study's authors, the decline in mitochondrial function in humans is visible during aging, and can lead to age-related diseases.

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<p>  "This mouse model should provide an unprecedented opportunity for the development of preventive and therapeutic therapeutic strategies to increase mitochondrial functions for the treatment of cutaneous and capillary pathology badociated with aging and other human diseases in which Mitochondrial dysfunction plays a significant role, "said Keshav Singh, a professor at the University of Alabama in Birmingham, United States.
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<p>  For the study, published in the journal Cell Death & Disease, the team added the antibiotic doxycycline – used to treat infections caused by bacteria and protozoa – to food or to drinking water to cause mutation of mitochondrial DNA because the enzyme to replicate the DNA becomes inactive.
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Say yes to water, no coffee …

Summer-Ready

March 24, 2018

The summer brings many digestive problems. Not only do high temperatures make us sweat more, but they also reduce our immunity, so be sure to eat well this season.

According to Kirti Chadha, head of global reference laboratories, Metropolis Healthcare Ltd., "the summer brings the majority of digestive-related diseases, and considering the rising temperatures each year, it is very important to manage our eating habits to avoid gastric diseases.

Here are some Chadha tips for keeping your stomach healthy this summer:

They found that, the mice showed gray hair, reduced hair density, hair loss, slowed movements and lethargy in four weeks. Wrinkled skin was observed four to eight weeks after induction of the mutation, and females had more severe skin wrinkles than males.

Inversion of the mutation restores mitochondrial function, as well as cutaneous and capillary pathology.

However, little change was observed in other organs when the mutation was induced, suggesting an important role for mitochondria in the skin compared to other tissues.

"This suggests that the epigenetic mechanisms underlying mitochondrial nucleus crosstalk must play an important role in restoring the normal skin and hair phenotype," said Singh.

The Ultimate Health Guide: 6 Foods to Keep Cholesterol …

The Call of Cholesterol

March 20, 2018

By Ayush Rekha

The first step to having healthy cholesterol levels is examining your diet.

Here are some foods that can help keep your lipid profile in the desired range.

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