An earlier dinner could reduce the risk of some cancers "CBS Boston

(CNN) – People who eat breakfast before 9pm – or at least two hours before going to sleep – have a 20% lower risk of bad and prostate cancer than those who eat after 22 hours. "The mechanisms are unclear," said Dr. Manolis Kogevinas, research professor at the Barcelona Institute for Global Health in Spain and lead author of a new study on the subject. . "What we know from experimental studies is that we are conditioned to function in different parts of the day – we – not just humans but all living organisms – have evolved in time differently from day and night. The study, published Tuesday in the International Journal of Cancer, followed 621 people with prostate cancer and 1,205 with bad cancer., As well as 872 men and 1,321 women without cancer. "

cancer, known as a control group, randomly selected in primary health centers across Spain.

The authors examined the lifestyle and chronotype of each person, or the preference to be a bird early or one night owl, asking them about the time they ate meals and their sleeping habits.The participants also completed questionnaires about their eating habits and about the prevention recommendations of the ancer such as physical activity and limiting the consumption of alcohol.

The researchers said that the effect of the supper-sleep interval was more marked. and in those who were morning-type with bad and prostate cancer.

About 27% of bad cancer patients followed cancer prevention recommendations, compared with 31% of the control group. The researchers interviewed the two types of groups twice, asking them about work and weekend patterns when they were 40 years old (or their current age, if they were younger) and about what they were doing. they did it every year. Before their cancer diagnosis or before their interview.

Although 7% of subjects also had snacks after supper, the study focused on full meals, says Kogevinas

. badociated with night work and disruption of the circadian rhythm or sleep-wake cycle of a person, explained Kogevinas. In 2007, the International Agency for Research on Cancer of the World Health Organization categorized shift work that disrupts circadian rhythm as a health risk that can cause cancer in humans. However, people who performed night work were not included in the new study.

The results of the study are quite consistent with previous research, said Catherine Marinac, a researcher at the Dana-Farber Cancer Institute. involved in the study. Marinac's own research suggests that eating in harmony with the body's natural clock can help reduce the risk of bad cancer recurrence among survivors.

"Population studies have shown that people who eat late at night have rates of obesity profiles," said Marinac. "And in particular, we found that people who have longer night-time fasting, which may involve less eating late, have better blood sugar control and a lower risk of cancer recurrence. treating glucose are mechanistic factors that link late-life diets to cancer risk, "she explains.

Many issues that are not considered in the new study can influence outcomes, has said Dr. Ganesh Palapattu Oncology at the University of Michigan Medical School, who was not involved in the research.For example, the study reports the educational status of the subjects, but not the 39, information about their work and their stress.

"I'm not sure it would be what I would call changing behavior or changing behavior in any way at this time." Palapattu. "On this study, I'm not going to tell patients to eat earlier or sleep later."

Both groups ate similar diets, and the researchers did extensive badyzes comparing the results and confirming that they were due to Kogevinas warned that although the findings of the study were Based on solid biological evidence, the data is still new. We need to study more populations in different contexts, outside of Spain, where people tend to dine later than other countries.

It will be after reproducing these results elsewhere and in large groups that recommendations can be made. Kogevinas said, "My general philosophy with this stuff is always for patients not to overreact to these studies, to continue doing things that are known to be hopeful and healthy. Palapattu said, "Do not smoke. Try to maintain your ideal body weight. Regular exercise. To wear a helmet. Do not send text and drive. Wear a seatbelt. "

Still, the new discoveries are intriguing," he noted.

"Not only are you what you eat," Palapattu said. "You're like you're eating, and it's very likely that you when you eat. "

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