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Australian and British researchers found mice with surviving pancreatic cancer much longer after being treated with cannabidiol with a commonly used chemotherapeutic agent.
The pancreas is an organ that helps the body to digest food According to the Cancer Council of Australia, pancreatic cancer is the tenth most common cancer in men and the ninth most common cancer common among women in Australia; However, it is the fifth most common cause of cancer deaths in general.
It is estimated that 3,364 new cases of pancreatic cancer will be diagnosed in Australia only this year.
The prognosis for many patients is not good. survival rate of only 5%. The life expectancy of pancreatic cancer patients has changed little over the past four decades.
With such survival rates, there has been a lot of research on extending patients' lives – and part of the answer could be non-psychoactive. cannabinoid called cannabidiol (CBD), which is widely studied for its potential to treat or handle a wide variety of conditions.
In research conducted by Curtin University and researchers at Queen Mary University in London, the results of mouse tests with a form of cancer very similar to that of pancreatic cancer in humans is pretty amazing.
".. KPC mice treated with a combination of the antagonist GPR55 Cannabidiol (CBD) and gemcitabine (GEM, one of the most used drugs to treat PDAC), survived nearly three times more a long time compared to mice treated with the vehicle or GEM alone, "say the researchers.
PDAC means Pancreatic ductal adenocarcinoma.
If t its success in mice is reproduced at home. man, a treatment could be available relatively quickly.
"Cannabidiol is already approved for clinical use, which means that we can quickly test this in human clinical trials" Marco Falasca. "If we can reproduce these effects in humans, Cannabidiol could be used in cancer clinics almost immediately, compared to waiting for the authorities to approve a new drug. "
Professor Falasca is currently working with Zelda Therapeutics (ASX: ZLD) on the development of treatments for life-threatening diseases, including pancreatic cancer.
The full article of the researchers was published in the journal Oncogene
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