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To control blood glucose levels, people with type 1 diabetes rely on daily injections of insulin, which can result in discomfort due to needle sticks and seizures. side effects over the years. But a new discovery, made by researchers at Harvard University in the United States, promises to improve the quality of life for these people: it's an insulin pill.
The study of this new approach, published by the journal Proceedings of the National Academy Society (PNAS) was to carry insulin in an ionic liquid with choline and acid geranic. The mixture was encapsulated in a stomach acid resistant material and injected into the throat of six rats, which showed a rapid reduction in blood glucose.
"Once ingested, insulin undergoes several obstacles before it is absorbed effectively into the chain.Our approach is like a knife from the Swiss army, where a pill has the tools to make faced with each of the obstacles encountered, "said Samir Mitragotri, one of the study's authors and a professor at Harvard University.
According to experts, the drug is biocompatible, easy to manufacture and can be stored for up to two months at room temperature without breaking down – the validity is higher compared to the injectables available on the market.But there is still a long way to go before the drug pill. insulin is commercialized: future plans include new tests on animals and hopefully on humans Diabetes is a metabolic syndrome of multiple origin, due to lack of insulin and / or the inability of insulin to exercise properly, resulting in increased glucose (sugar) in the blood. Diabetes occurs because the pancreas is not able to produce enough hormone to meet the needs of the body, or because the hormone is not able to act properly (insulin resistance). Insulin promotes the reduction of blood sugar by allowing the sugar in the blood to enter the cells to be used as a source of energy. Therefore, if there is a lack of this hormone, or even if it does not work properly, there will be an increase in blood sugar and therefore diabetes. To find 10 essential nutrients to control the disease by clicking here
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