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One of the features that make cancer very deadly is that it can spread throughout the body, affecting not only the organ in which it appears, but also the body whole.
In medical terms, we speak of metastasis. But now, a new treatment based on bad cancer cells – and until now only tested on mice – has yielded excellent results to prevent this phenomenon.
The findings come from a research conducted by scientists from the Department of Biomedicine at the University of Basel, Switzerland, published in the journal Cancer Cell.
. Cell Growth
Cancer cells can usually alter their properties. molecules to adopt the characteristics of other types of cells and thus separate from the original group. Once released, they can migrate to other parts of the body through the bloodstream
. This process, called the epithelial-mesenchymal transition, is essential for embryonic development. And when it comes to cancer cells, it is the most powerful weapon to spread the disease.
In their studies, the group of scientists from the Swiss university could use this process to act against the tumor cell itself, preventing it from entering the bloodstream.
Indeed, when cells change their properties to initiate epithelial-mesenchymal transition, they also become more mutable.
Scientists have attributed to rodents used in research a combination of two drugs: one for type 2 diabetes, called rosiglitazone, and an inhibitor of the growth and spread of cancer cells, trametinib. Images
Fat cells do not go to other parts of the body but remain attached to the original cell group
According to research, the treatment showed that cancer cells were converted to fat instead of continuing the cell division that precedes the metastases.
The fat cells obtained were the same as ordinary fat cells, which can not The authors of the study hope that in the future, this therapy could be used in conjunction with chemotherapeutic treatments and prevent the growth of the tumor and its spread to other tissues. other organs or tissues.
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