Glycemic / insulinemic curve: reference and interpretation values

One of the most important and most interesting combinations of tests in the diagnosis and badessment of diabetes is the combination of glycemia and insulinemia (insulin level in the blood), a review called Glycemic and Insulinemic Curve In this article, we will talk more about the importance of performing both these dosages at the same time and what valuable information this type of. laboratory examination can provide us.

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Browse this topic:

1. What is the Glycemic Curve?
2. What is the Glycemic Curve?
3. What is the glycemic curve?]
4. What is the insulinemic curve?
5. What is the role of insulin in glucose?
6. Reference values ​​
7. Insulin curve: interpretation [19659011] What is the Glycemic Curve? Glycemic Curve or TOTG in an Arti [19] 659002] The glucose curve, also known as the oral glucose tolerance test, is an examination where a standard amount (75 grams) of dextrose glucose will be given to the patient to inhale orally before [19659002] Next, blood sugar levels (glucose) will be measured during fasting, 1 hour and 2 hours after ingestion of this glucose load. With these data, we can make a blood glucose curve over time.

   This important review provides us with concrete data on how our body responds to glucose ingestion. A normal person should have a not too high rise in blood glucose 1 and 2 hours after ingestion. To evaluate this, we have reference values ​​for diagnosing diabetes in adults.

   According to the Brazilian Diabetes Society (SBD) and the World Health Organization (WHO), these values ​​are considered normal for the glycemic curve (19659021) Diabetes Diagnosis Diabetes ] Diabetes Diabetes Diabetes Diabetes Mellitus Equal to or greater than 200

   What is the insulinemic curve?

   Understanding the glycemic curve, it is easy to understand what is the insulinemic curve or the insulin curve: this is nothing more than

   The curve of insulin is very important in the badessment of suspected diabetes or to check the response to a specific treatment. In the case of type 2 diabetes, there is an increase in insulin levels with glucose

   What is the role of insulin in blood glucose?

   Insulin has several actions in the different cells of our body. However, its main activity is to remove the glucose that is in the blood after absorption by the diet and load it into the cells so that they can use it as energy.

   Now, you may ask yourself: ""

   This is because in type 2 diabetes there is what is called resistance to the disease. insulin ]: due to a number of factors (the main ones being overweight and lack of physical activity – sedentary lifestyle), the cells of our body (mainly muscles and the liver) "close the door" to the action of insulin It is as if the doors of the cells are getting closer to the entrance of more glucose simply because they "think" that they already have enough energy inside of them.

   See also: Types of Insulin in the Treatment of Diabetes

   Curve Glic Emica and Insulinemica: Reference Values ​​

   In the case of the glycemic curve, in diabetes, it will exceed the values ​​mentioned here -above. The reference values ​​for the insulin curve are as follows: Time Insulin levels Fasting Less than 25 mIU / L 30 min after the # 39, ingestion of glucose 1 hour after glucose ingestion 18-276 mIU / L 2 hours after glucose ingestion 16-166 mIU / L 3 hours or more after glucose ingestion Less than 25 mIU / L

   Insulinemia curve: interpretation

   Abnormal insulin levels may indicate resistance to l & # 39; insulin. This means that insulin can not properly transport the sugar in the cells and, as a result, the pancreas tries to compensate for this problem by secreting an excess of insulin. Conditions badociated with insulin resistance include:

   • Type 2 diabetes mellitus (except advanced phase, when the pancreas can no longer secrete insulin);
   • obesity;
   • acromegaly;
   • Cushing's syndrome

   • The insulin-secreting tumor is the most common cause of insulin secretion in patients with insulin secretion.

   • Mutations in the insulin gene

   In some cases, excess insulin can also be caused by an insulin secreting tumor. Hepatic or cardiac insufficiency may decrease the excretion of insulin and also cause high blood levels

   Reduced levels of insulin may indicate conditions where hormone production is impaired :

   • Type 1 Diabetes mellitus
   • Chronic pancreatitis
   • Autoimmune destruction of pancreatic islets
   • Patients with pancreatectomy