Why is fentanyl so deadly?



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<p clbad = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "Pittsburgh rapper Mac Miller released his fifth album, To swim, before his death at 26 years earlier this fall. "data-reactid =" 22 ">Pittsburgh rapper Mac Miller released his fifth album, To swim, before his death at 26 years earlier this fall.

<p clbad = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "A coroner recently stated that his death was an accidental overdose of fentanyl, a fast-acting opioid 100 times more potent than morphine."data-reactid =" 23 ">A coroner recently stated that his death was an accidental overdose of fentanyl, a fast-acting opioid 100 times more potent than morphine.

<p clbad = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "Miller joins an incredibly long list of people who have been unconsciously exposed to a potentially lethal substance, a substance that puts Canada in crisis. "data-reactid =" 24 ">Miller joins an incredibly long list of people who have been unconsciously exposed to a potentially lethal substance, a substance that puts Canada in crisis.

<p clbad = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "More than 8,000 apparent opioid deaths have been reported in Canada between January 2016 and March 2018, according to the report. federal government. Between January and March of this year, there were at least 1,036 opioid-related deaths, 94% of which were accidental; 73% of those involved fentanyl. "data-reactid =" 25 ">More than 8,000 apparent opioid deaths have been reported in Canada between January 2016 and March 2018, according to the report. federal government. Between January and March of this year, there were at least 1,036 opioid-related deaths, 94% of which were accidental; 73% of those involved fentanyl.

<p clbad = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = ""Fentanyl is extremely toxic," says Dr. Mark Lysyshyn, Medical Officer of Health for Vancouver Coastal Health. "A small amount has a powerful effect. It is a very dangerous product."data-reactid =" 26 ">"Fentanyl is extremely toxic," says Dr. Mark Lysyshyn, Medical Officer of Health for Vancouver Coastal Health. "A small amount has a powerful effect. It is a very dangerous product.

<p clbad = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "SEE ALSO: The death of rapper Mac Miller ruled that an accidental overdose of fentanyl, cocaine and alcohol"data-reactid =" 27 ">SEE ALSO: The death of rapper Mac Miller ruled that an accidental overdose of fentanyl, cocaine and alcohol

<p clbad = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "Fentanyl has a legitimate use in medical settings: it is used for anesthesia and the treatment of severe long-term pain, often in cancer patients. When prescribed by a doctor, it is administered by injection, transdermal patch or lozenges. Monitored closely in a clinical setting, it can be effective and safe."data-reactid =" 28 ">Fentanyl has a legitimate use in medical settings: it is used for anesthesia and the treatment of severe long-term pain, often in cancer patients. When prescribed by a doctor, it is administered by injection, transdermal patch or lozenges. Monitored closely in a clinical setting, it can be effective and safe.

<p clbad = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "It works by binding to the body's opioid receptors, which are in areas of the brain that control pain and emotions. Like heroin, morphine and other opioid medications, when fentanyl binds to these receptors, dopamine levels in the brain's reward centers increase, resulting in a state of relaxation and euphoria, according to the Institute. National Anti-Drug Policy."data-reactid =" 29 ">It works by binding to the body's opioid receptors, which are in areas of the brain that control pain and emotions. Like heroin, morphine and other opioid medications, when fentanyl binds to these receptors, dopamine levels in the brain's reward centers increase, resulting in a state of relaxation and euphoria, according to the Institute. National Anti-Drug Policy.

<p clbad = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "However, here is why it is so dangerous: Opioid receptors are also found in areas of the brain that control breathing. High doses of opioids, especially forms as potent as fentanyl, can cause complete arrest of breathing, which can cause brain damage or death. "data-reactid =" 30 ">However, here is why it is so dangerous: Opioid receptors are also found in areas of the brain that control breathing. High doses of opioids, especially forms as potent as fentanyl, can cause complete arrest of breathing, which can cause brain damage or death.

<p clbad = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "Two milligrams of pure fentanyl – about the size of four grains of salt – are enough to kill an average adult."data-reactid =" 31 ">Two milligrams of pure fentanyl – about the size of four grains of salt – are enough to kill an average adult.

<p clbad = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "Fentanyl sold in the street can be mixed with heroin or other drugs, which greatly increases its toxicity and its potential dangers."data-reactid =" 32 ">Fentanyl sold in the street can be mixed with heroin or other drugs, which greatly increases its toxicity and its potential dangers.

<p clbad = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "It is odorless and tasteless and therefore difficult to detect, according to the RCMP. It can be found in the form of powder, liquid and blotter. Fentanyl is also often presented in tablet form and sold in the street under the name of Oxycodone, a popular painkiller. In Canadathese counterfeit pills are often green in color and are labeled "CDN 80"."data-reactid =" 33 ">It is odorless and tasteless and therefore difficult to detect, according to the RCMP. It can be found in the form of powder, liquid and blotter. Fentanyl is also often presented in tablet form and sold in the street under the name of Oxycodone, a popular painkiller. In Canadathese counterfeit pills are often green in color and are labeled "CDN 80".

<p clbad = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "Fentanyl carries all sorts of nicknames, including Apache, Chinese Girl, Chinese White, Dance Fever, Friend, Goodfella, Green Beans, Jackpot, Murder 8, Shady 80s, TNT and Tango and Cash."data-reactid =" 34 ">Fentanyl carries all sorts of nicknames, including Apache, Chinese Girl, Chinese White, Dance Fever, Friend, Goodfella, Green Beans, Jackpot, Murder 8, Shady 80s, TNT and Tango and Cash.

<p clbad = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "A single kilogram of fentanyl, worth a few thousand dollars, can be reduced in more than 100,000 tablets, which are worth millions on the street, according to the US Drug Enforcement Agency."data-reactid =" 35 ">A single kilogram of fentanyl, worth a few thousand dollars, can be reduced in more than 100,000 tablets, which are worth millions on the street, according to the US Drug Enforcement Agency.

<p clbad = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "According to the US Drug Enforcement Agency, China is the main source of illicit fentanyl. Organized crime and independent resellers can buy the drug online and transit it across the border; The RCMP says that many Chinese manufacturers even offer free replacements if the first shipment is seized."data-reactid =" 36 ">According to the US Drug Enforcement Agency, China is the main source of illicit fentanyl. Organized crime and independent resellers can buy the drug online and transit it across the border; The RCMP says that many Chinese manufacturers even offer free replacements if the first shipment is seized.

<p clbad = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "SEE ALSO: TMZ claims that the "free" oxycodone of Demi Lovato mixed with fentanyl: what does this mean exactly?"data-reactid =" 37 ">SEE ALSO: TMZ claims that the "free" oxycodone of Demi Lovato mixed with fentanyl: what does this mean exactly?

<p clbad = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "Drug testing projects in Vancouver – including fentanyl test strips and infrared spectrometers that badyze drug mixtures to detect fentanyl – have led to a better understanding of the contamination of illicit substances. Lysyshyn says that fentanyl is most often mixed with opioids, such as heroin. Recent tests have shown that less than five percent of cocaine and crystal meth are contaminated and that even lower levels have been observed in MDMA and ketamine. "data-reactid =" 38 ">Drug testing projects in Vancouver – including fentanyl test strips and infrared spectrometers that badyze drug mixtures to detect fentanyl – have led to a better understanding of the contamination of illicit substances. Lysyshyn says that fentanyl is most often mixed with opioids, such as heroin. Recent tests have shown that less than five percent of cocaine and crystal meth are contaminated and that even lower levels have been observed in MDMA and ketamine.

<p clbad = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = ""It's a totally unregulated market and, as a result, many things can happen," says Lysyshyn. "People can deliberately contaminate drugs – add them to heroin – or replace one drug with another and sell fentanyl instead of heroin. If someone wants to buy cocaine but you have a different white powder, you can sell it because you want to make money. Or you can make a mistake. You may be thinking of giving cocaine to someone, but since you are under police surveillance and you have to complete the transaction quickly, you are giving him some fentanyl. People are now using more dangerous drugs than before. It is a crisis of contamination. ""data-reactid =" 39 ">"It's a totally unregulated market and, as a result, many things can happen," says Lysyshyn. "People can deliberately contaminate drugs – add them to heroin – or replace one drug with another and sell fentanyl instead of heroin. If someone wants to buy cocaine but you have a different white powder, you can sell it because you want to make money. Or you can make a mistake. You may be thinking of giving cocaine to someone, but since you are under police surveillance and you have to complete the transaction quickly, you are giving him some fentanyl. People are now using more dangerous drugs than before. It is a crisis of contamination. "

<p clbad = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "Many users start with legitimate prescriptions to manage pain, but eventually become addicted and turn to the opiate black market to feed their addiction. A recent United Nations report found that Canada consumes the most prescription opioids per capita of any country in the world. "data-reactid =" 44 ">Many users start with legitimate prescriptions to manage pain, but eventually become addicted and turn to the opiate black market to feed their addiction. A recent United Nations report found that Canada consumes the most prescription opioids per capita of any country in the world.

<p clbad = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "Canada desperately needs a lot more doctors trained in addiction, said Dr. Evan Wood, director of the Center for Addiction in British Columbia at St. Paul's Hospital in Vancouver. He cites the case of B.C. Jordan Miller, died in 2014 at the age of 25 from an accidental overdose. His mother, Leslie McBane, publicly told his story, telling the media that oxycontin had been prescribed him for pain resulting from an injury at work and that he had become addicted to it. He repeatedly told his doctor that he needed help getting rid of his painkiller, but had not received any help. "data-reactid =" 45 ">Canada desperately needs a lot more doctors trained in addiction, said Dr. Evan Wood, director of the Center for Addiction in British Columbia at St. Paul's Hospital in Vancouver. He cites the case of B.C. Jordan Miller, died in 2014 at the age of 25 from an accidental overdose. His mother, Leslie McBane, publicly told his story, telling the media that oxycontin had been prescribed him for pain resulting from an injury at work and that he had become addicted to it. He repeatedly told his doctor that he needed help getting rid of his painkiller, but had not received any help.

<p clbad = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "The College of Physicians and Surgeons later concluded that the physician had failed in the young man by "prescribing combinations of opioids" and "taking no definitive action when presented with evidence of 39, opioid abuse ". McBane then co-founded Moms Stop the Harm working for harm reduction changes in drug policies."data-reactid =" 46 ">The College of Physicians and Surgeons later concluded that the physician had failed in the young man by "prescribing combinations of opioids" and "taking no definitive action when presented with evidence of 39, opioid abuse ". McBane then co-founded Moms Stop the Harm working for harm reduction changes in drug policies.

<p clbad = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "SEE ALSO: Fentanyl is badociated with thousands of deaths a year, so why are doctors still prescribing it?"data-reactid =" 47 ">SEE ALSO: Fentanyl is badociated with thousands of deaths a year, so why are doctors still prescribing it?

<p clbad = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = ""Most health care providers who should diagnose and treat addiction do not know it and do not know how to do it," says Wood. "In a situation where family doctors may prescribe opioids for pain relief, they need training to prescribe drugs for opioid addiction, such as Suboxone. We have pathologists, pulmonologists, gastroenterologists, cardiologists, but we have not invested in training health care providers in evidence-based drug treatment. ""data-reactid =" 48 ">"Most health care providers who should diagnose and treat addiction do not know it and do not know how to do it," says Wood. "In a situation where family doctors may prescribe opioids for pain relief, they need training to prescribe drugs for opioid addiction, such as Suboxone. We have pathologists, pulmonologists, gastroenterologists, cardiologists, but we have not invested in training health care providers in evidence-based drug treatment. "

<p clbad = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "Drug control, where people can have their drugs tested for the presence of fentanyl, needs to be more widely available, Wood said, as well as recovery services. "Treating this disease as a criminal justice problem makes it very difficult for people to make themselves known and to get help."data-reactid =" 49 ">Drug control, where people can have their drugs tested for the presence of fentanyl, needs to be more widely available, Wood said, as well as recovery services. "Treating this disease as a criminal justice problem makes it very difficult for people to make themselves known and to get help.

<p clbad = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = ""Treatments such as heroin prescription need to be intensified for people rooted in the street; we know it's profitable, "he adds. "Rehabilitation services that help people with jobs by helping them get out of a life of dependency need to be scaled up. Why is this not happening? Because there is no skilled workforce of care providers. ""data-reactid =" 50 ">"Treatments such as heroin prescription need to be intensified for people rooted in the street; we know it's profitable, "he adds. "Rehabilitation services that help people with jobs by helping them get out of a life of dependency need to be scaled up. Why is this not happening? Because there is no skilled workforce of care providers. "

<p clbad = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "To prevent overdose deaths, it is essential that people who use illicit drugs do not eat alone and, if possible, go to a supervised injection site or to an overdose prevention site, says Lysyshyn. People should never mix opioids with alcohol or other substances. Users or those in contact with them should also carry naloxone kits for use if necessary. the drug quickly reverses the effects of overdose of opioids. And he says people should know what an overdose looks like in order to get emergency medical care when needed. "data-reactid =" 51 ">To prevent overdose deaths, it is essential that people who use illicit drugs do not eat alone and, if possible, go to a supervised injection site or to an overdose prevention site, says Lysyshyn. People should never mix opioids with alcohol or other substances. Users or those in contact with them should also carry naloxone kits for use if necessary. the drug quickly reverses the effects of overdose of opioids. And he says people should know what an overdose looks like in order to get emergency medical care when needed.

<p clbad = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = ""People need to know that it's safe to dial 911, that they will not be stopped if there's drugs on the premises, or if they admit to using them," says Lysyshyn. "In case of overdose of opioids, people become sleepy. they can fall asleep or lose consciousness. Their lips may turn blue, their skin may turn gray if they do not get enough oxygen to the brain. They could be out of breath. ""data-reactid =" 52 ">"People need to know that it's safe to dial 911, that they will not be stopped if there's drugs on the premises, or if they admit to using them," says Lysyshyn. "In case of overdose of opioids, people become sleepy. they can fall asleep or lose consciousness. Their lips may turn blue, their skin may turn gray if they do not get enough oxygen to the brain. They could be out of breath. "

<p clbad = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = ""This very dangerous product still exists, people still use it and they still use it in high-risk situations, only behind closed doors," he says. "The solution is ultimately to get rid of stigma by decriminalizing drug use, regulating the supply of drugs so that this dangerous drug is no longer available." "data-reactid =" 53 ">"This very dangerous product still exists, people still use it and they still use it in high-risk situations, only behind closed doors," he says. "The solution is ultimately to get rid of stigma by decriminalizing drug use, regulating the supply of drugs so that this dangerous drug is no longer available."

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