Even low levels of air pollution increase the risk of diabetes



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Exposure to air pollution can contribute to millions of new cases of diabetes worldwide each year, according to a study published in The Lancet Planetary Health

"Our research shows a significant link between air pollution and diabetes " Ziyad Al-Aly, MD, Assistant Professor of Medicine at the University of Washington and the principal author of the study, said in a press release. "We have found an increased risk even at low levels of air pollution currently considered safe by the US Environmental Protection Agency and the WHO.This is important because many groups Industry pressure argues that current levels are too stringent and should be relaxed.The evidence shows that current levels are not yet safe enough and need to be tightened. "

To rate the badociation from exposure to particles with aerodynamic diameter less than 2.5 μm (PM 2.5 ) with diabetes, the researchers conducted a longitudinal cohort study consisting of 1,729,108 US veterans who had no previous diagnosis of diabetes All participants were followed for a median of 8.5 years and proportional risk models of Cox were used.

In the press release, researchers also linked patient data to data from NASA's ground-based air monitoring systems and NASA space satellites.

To expand the scope of the study, data from the annual study on the global burden of disease conducted to estimate the annual cases of diabetes and the effect of pollution on the loss of Years of healthy life.

After adjusting for socio-demographic and health characteristics, researchers found that an increase of 10 μg / m³ PM 2.5 in the US Veterans cohort was badociated with increased risk (HR = 1.15, CI%, 1.08-1.22) and also with an increased risk of death as a control of positive outcomes (HR = 1.08, 95% CI, 1.03- 1.13).

Overall, air pollution contributed to about 3.2 million (95% uncertainty interval) [UI] 2.2-3.8) cases of diabetes, about 8.2 million (95% IU, 5 , 8-11) lost healthy years and 206,105 (95% UI, 153,408-259,119) diabetes-related deaths in 2016, according to researchers It was also determined that the risk of diabetes-related pollution varies geographically and is more important in low income countries due, in part, to a lack of environmental resources and air sanitation policies. moderate risk of diabetes linked to pollution, "according to the Liberation.

"In the last two decades, there has been research on diabetes and pollution," Al-Aly said in a statement. "We wanted to put the pieces together for a broader and stronger understanding."

The results follow several studies that have suggested a link between air pollution and the risk of diabetes. As previously described Endocrine Today prolonged ambient exposure, especially exposure to nitrogen dioxide and PM 2.5 increases the risk of developing type 2 diabetes in Hispanic children overweight or obesity . After adjusting for confounding factors and body fat percentage, higher exposures to nitrogen dioxide and PM 2.5 had negative effects on the development of diabetes risk factors type 2, including insulin sensitivity index. Fatigue of beta-cell functions was also evident with prolonged exposure to ambient air pollution. – by Melissa J. Webb

Disclosure s :
The authors do not report any relevant financial information.

  

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