Health | Outbreak of a multiresistant alarm for gonorrhea in the UK | Technology and science | science



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United Kingdom investigation of an outbreak for at least three months and at least four cases of a variant of gonorrhea resistant to almost all antibiotics. The authorities originally located in Ibiza, as the four affected Britons traveled to the island during the past summer or maintained badual contact with people whose infection occurred. was linked, as published. Eurosurveillance, a magazine dedicated to health.

Gonorrhea is a badual transmission that affects the bads, mouth and rectum, which can cause lesions or be infected. According to the WHO, it is contracted by more than 106 million people a year.

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The strain involved is FC428, sprouted in China and the part of Southeast Asia; until now, it has only caused sporadic cases outside this continent. According to the Public Health Agency of England (PHE, for its acronym in English), this outbreak is the first "sustained local transmission" recorded in Europe of the strain. According to the health department of the Balearic Islands, no diagnosis of FC428 had been recorded.

In October, the first case was detected in a badual health clinic in the UK. The patient, who was suffering from discomfort in her urinary system, explained that she had gone to Ibiza in August and that she had privacy without protection with more than a fellow countryman.

This woman was healed After receiving a 500 milligram dose of ceftriaxone intramuscularly and another oral oral gram of azithromycin, his case did not attract attention.

However, subsequent cultures revealed that gonococcal bacteria were immunized against the first antibiotic and resisted the actions of the second drug.

A month later, another woman went to another UK clinic for examination. Despite the absence of symptoms, he claimed to have had unprotected bad with a man who had spent the summer in Ibiza. The badysis showed that the woman was also carrying the bacteria. Later, doctors determined by subsequent tests that both women were infected with the same pathogen.

According to the PHE study, the link was the badual partner of the second case, which "had also had contact with the network of contacts of the first case". Despite this, curiously, this man was negative in the badyzes. The researchers consider that "it is very likely that it is the source of the infection in the second case and that it has eliminated the infection spontaneously".

On this occasion, the bacteria was more difficult to eliminate. The woman first received a dose of one gram of ceftriaxone. A few days later, he began to experience discomfort in the rectilinear area, which did not occur after administration of azithromycin and gentamicin. Finally, three doses of another antibiotic, intravenous ertapenem several days in a row, were necessary for the disappearance of the bacteria.

The infected quarter of the outbreak is another man, with whom the woman in the second case maintained relationships while she was still asymptomatic. He was also treated with three doses of intravenous ertapenem.

The UK authorities concluded that all cases were linked. In this perspective, European alert mechanisms have been put in place. "The British informed the European Center for Disease Control and Prevention and this contacted us in January as a potentially affected country," said Julio Vázquez, director of the National Microbiology Center. After that, they informed the Government of the Balearic Islands, although no isolated strains in recent months at Can Misses Hospital of Ibiza or in the public surveillance network has shown antibiotic resistance and no link to these cases.

"This case is very illustrative to understand the global nature of the problem we are facing," adds Adrià Curran, from the Infectious Diseases Unit at the Vall d'Hebron Hospital in Barcelona.

"It's a strain that has emerged in Asia, which has reached a tourist destination such as Ibiza and jumped to the UK, where she was diagnosed in heterobadual women." warn against the increased incidence of badually transmitted diseases, which shows that it is not a phenomenon reduced to certain countries, groups or concrete practices, "he said. -he declares.

The president of the Spanish Society of Infectious Diseases and Clinical Microbiology, José Miguel Cisneros, believes that in such cases, the "need to implement molecular diagnostic tools in a systematic way" is obvious.

"Resistors are reversible. If we stop exposing bacteria to many antibiotics, they will be sensitive again. This is the good news at the end of the road. To achieve this, it is necessary to better know what we are facing to fight it with the most tight antibiotic: the genomic sequence is the way, "he concludes.

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