The University of Tel Aviv creates a melanoma vaccine that works in mice



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JERUSALEM (Sputnik) – A team of researchers from the Tel Aviv University (TAU) has created a vaccine to prevent the development of primary tumors and metastases in melanomas, effective in mice.

The study, published in the journal Nature Nanotechnology, demonstrates "that it is possible to produce an effective nanovaccine" from a nanoparticle, according to a statement by Professor Ronit Satchi-Fainaro, the author of the report. one of the research coordinators and head of the department of physiology and medicine. Pharmacology TAU.

"Our research opens the door to a completely new approach, the vaccine approach, for the effective treatment of melanoma, even at the most advanced stages," said Ronit Satchi-Fainaro.

According to her, her research could develop other cancer vaccines. To achieve melanoma, one of the most aggressive skin cancers, "the researchers took advantage of small particles of about 170 nanometers in size, made up of a biodegradable polymer".

"Nanoparticles have been used as known vaccines against virus-transmitted diseases," Satchi-Fainaro said. "They stimulated the immune system of mice and immune cells learned to identify and attack melanoma cells".

If this new development works by applying it in the near future to patients with melanoma, the door could be opened to a new treatment for the disease in general, beyond surgery, chemotherapy , radiotherapy and immunotherapy.

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