She was 62 years old.
CNN tried to reach his family.
Nickerson's last actor credit dates back to 1978. Before leaving Hollywood, she participated in "The Brady Bunch" and the cult TV series "Dark Shadows".
His role in Roald Dahl's iconic adaptation remains his most famous work.
In 2011, some of the film's key actors came together for an episode of "Top Chef: Desserts," which challenged the contestants to create a world of edible wonder.
At that time, Nickerson joked that playing the role did not make her sick of chewing gum, but that her dental health led to her finally giving up.
"When did you give up?" the interviewer asked.
"When I came back and I had 13 cavities," she said.
The actors also evoked the so-called Wonka effect, a term they attributed to the reaction of the fans.
"Listen, I mean, we're the lucky ones, we're here, we really have to see it and experience it," Nickerson said. "The first thing people do when they find out who we are, is that they smile."