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United States Food and Drug Administration issued a warning on Thursday following the death of a patient who received a stool transplant containing a drug-resistant bacterium.
Fecal transplants are used to treat Clostridium difficile (It's hard) Infection in patients who have not responded to standard treatment options. The treatment involves transferring the stool of a healthy person to the intestines of an infected person in order to introduce good bacteria.
Two adults with a complex immune system who received a transplant from the same donor developed invasive infections caused by Escherichia coli (E. coli) producing extended spectrum beta-lactamase (ESBL), the FDA said.
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The stool of the donor was not tested for drug-resistant bacteria before the procedure, the FDA noted. After patients became ill, a stored stool donor sample was tested and found to contain the E. coli present in both patients.
As a result of these adverse reactions, the FDA requires that potential donors be asked questions and that all donor stools be tested for drug-resistant bacteria.
C. diff causes nearly 500,000 diseases each year and can affect people of all ages, according to the Centers for Disease Control and Prevention.
Antibiotic resistance is also one of the biggest public health problems of our time, the CDC said. Every year in the United States, at least 2 million people become infected with antibiotics and at least 23,000 people die, according to a report by the CDC.
Read or share this story: https://www.usatoday.com/story/news/health/2019/06/13/fda-drug-resistant-bacteria-fecal-transplant-kills-patient/1451580001/
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