They find a molecular key to delay the development of multiple sclerosis



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REFERENCE | Multiple Sclerosis Image taken from Cuba. CUBASI

Researchers from the University of the Basque Country (northern Spain) have found a molecular key to delay the progression of multiple sclerosis a finding published in the scientific journal EMBO Molecular Medicine. Multiple sclerosis is an autoimmune disease that attacks and destroys a structure called "myelin sheath" whose integrity is essential for the proper functioning of the brain and spinal cord.

The current treatment of the multiple sclerosis is based on the modulation of the activity of the immune system and prevents its cells from accessing and damaging the central nervous system. These therapies are effective in the early stages of the disease, but do not prevent their progression and progressive functional deterioration.

In the work that has just been published, it was possible to identify a receptor called P2X4 in microglial cells. anti-inflammatory, to reduce the damage in the multiple sclerosis and, most importantly, improve the body's own repair responses.

According to Dr. Maria Domercq, Department of Neuroscience of the UPV / EHU, who works in the research center Achucarro de Leioa, " we are faced with a discovery that opens a new path of pharmacological development for the treatment of the progressive phase of multiple sclerosis and with it ] we want to open a new door to improving the quality of life of people who suffer "

In this ambitious study, coordinated by inv Researchers from the Basque Country, professionals from the University of Hamburg in Germany and from the Institute of Functional Genomics of Montpellier have also collaborated. EFE

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