Japanese scientists use ultrasound to treat dementia in mice

A team of Japanese scientists revealed their success in using ultrasound to treat cognitive disorders in mice with vascular dementia and Alzheimer's disease, the most common form of dementia, and the application of ultrasound to the brain as a whole.

A team of cardiologists from Japan's Tohoku University led by Hiroaki Shimokara, a cardiologist, began submitting a group of mice to surgery that reduced blood flow to the brain and mimicked the effects of the Vascular dementia, the other group was designed by a genus The researchers then applied pulsed low intensity ultrasound (LIPUS) to the brain of animals of both groups, in 3 sessions of 20 minutes, and mice with dementia received treatments 3 times a day. For 5 days, mice with Alzheimer's were subjected to 11 days of sporadic treatment over a period of 3 months.

Behavioral tests indicated that ultrasound mice showed significant improvements in cognitive function during careful examination, in the expression of an enzyme involved in Mole angiogenesis, with an increase in protein that plays a key role in neuronal survival and growth.