[ad_1]
An international team of scientists has discovered a new protein complex that rebuilds damaged DNA, and in case of mutation, bad cancer cells resist chemotherapy based on PARP inhibitors.
According to the Medical Express website, scientists investigated bad cancer cells in which mutations occurred in the BRCA1 gene and used CrysperCase 9 to detect the genes responsible for the resistance of malignant tumors to the bad. olaparib and talaoparib
PARP, which inhibits the activity of polymerases -poly (ADP-ribose), a DNA repair system used by cancer cells to prevent death, in which case the method usual repair of the DNA is damaged.
The efficacy of PARP inhibitors has been shown to be mutated in the case of gene mutations encoding the SHLD1, SHLD2 and SHLD3 proteins, which form a complex badociated with DNA termini directly damaged. Chemotherapy aimed at inhibiting polymerase-poly (ADP-ribose).
We thank all our followers and we always promise to provide all that is better .. and to forward news from all sources of information and to facilitate their reading. Do not forget the IK work for our Facebook page and follow the latest news on Twitter.
Discover the cause of bad cancer development
Monday 23.07.2018 17:53 Follow us on the social networking sites of our site to receive new news permanently.
Source: Arab Yemen
[ad_2]
Source link
