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An HIV vaccine that has the potential to protect people around the world against the virus has yielded promising results.
The treatment, which aims to immunize against various strains of the virus, produced an anti-HIV immune response in tests on 393 people, a study in the Lancet found
It also protected some monkeys against a virus which is similar to HIV.
More tests are now needed to determine if the immune response produced can prevent HIV infection.
Approximately 37 million people worldwide are living with HIV or AIDS, and an estimated 1.8 million new cases each year.
But Despite Advances in HIV Treatment, An HIV Vaccine and Vaccine
Drug Preparation, or Pre-Exposure Prophylaxis, is Effective in Preventing HIV Infection, But, Contrary to to a vaccine, it must be taken regularly, even daily, to prevent the virus from settling [19659002] Inventing a vaccine has proven to be a huge challenge for scientists, in part because there is so much virus, but also because HIV is able to mutate to escape the attacks of our immune system.
Previous attempts at HIV vaccines were limited to specific strains. the virus found in some parts of the world.
But for this "mosaic" vaccine, scientists have developed a treatment consisting of different HIV viruses
The hope is that it could offer much better protection against the virus. In a randomized, double-blind, placebo-controlled trial, scientists tested various combinations of the mosaic vaccine in people aged 18 to 50 who did not have HIV and who were in good health.
Participants from the United States, Rwanda, Uganda, South Africa, and Thailand received four vaccines for 48 weeks
All vaccine combinations produced one response Anti-HIV Immunity and
Scientists also conducted a parallel study in which they administered a vaccine to rhesus monkeys to protect them from the simian immunodeficiency virus – an HIV-like virus that infects monkeys.
showed that the most promising in humans was found to protect 67% of the 72 monkeys from the disease.
"These results represent a milestone," said Dan Barouch, professor of medicine at Harvard Medical School and senior author of the study.
However, Professor Barouch also cautioned that the results should be interpreted with caution.
Although the vaccine has triggered a response in the immune system of people who took it, it is not clear if that would be enough. fight the virus and prevent infection.
"The challenges in the development of an HIV vaccine are unprecedented, and the ability to induce specific immune responses to HIV does not necessarily indicate that a vaccine will be used." It protects humans from HIV infection, "he added. Nevertheless, the promising results of the study mean that researchers will then test the treatment on 2,600 women in southern Africa who are at risk of contracting the disease – one of five vaccines to reach this stage of life. saying efficiency tests. Only one vaccine has already shown evidence of protection against HIV.
Published in the Daily Times, 9 July th 2018.
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