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It could be the outbreak of a vicious circle that affects people with type 2 diabetes: a drug that lowers blood sugar and slows the appetite of patients. The drug, which has now been tested in a clinical study at the University of Leipzig, first struck in humans. The study director, Michael Stumvoll, explains how the new product differs from previous products:
When patients have to inject insulin for a disease or get an insulin stimulating drug, most continue to increase. We put you in a vicious circle: you have diabetes because you are overweight. Against diabetes, they inject drugs that make them even more.
The new active ingredient, a type of double hormone, breaks this cycle. This mode of action also makes it interesting for another medical field – for the therapy of obesity. However, it is still speculative limits Stumvoll at the request of MDR knowledge, because in this area, the new preparation has not yet been studied – but that does not mean that a such "drug career" is excluded. Stumfast refers to Liraglutide, a parent of the new drug: "This drug has also been developed as an over-the-counter diabetic overweight drug and is now being treated for overweight and obesity. Adiposity only on the market. Years in the country. "
A drug that makes you slim?
The study, now published in the medical journal The Lancet, injected 112 patients at different doses for seven to 40 days. This should determine the optimal dosage and side effects. As Stumully admits, the most important thing is that this principle of action has struck for the first time in humans. People aged between 18 and 65 were examined in eleven establishments in Germany.
It is not really possible to evaluate the history of weights according to this period. To do this, studies should last more than two years, according to the endocrinologist from Leipzig. All participants improved blood sugar and weight, compared to control group participants. Side effects included mild nausea and increased heart rate. "Before the approval of the drug, it is now necessary to balance between the optimal effect and the minimal side effects," says Professor Stumvoll. He is waiting for the approval of the market in the coming years.
How common is type 2 diabetes and how many are affected?
More than 90% of all diabetic patients suffer from type 2 diabetes: they react less quickly to insulin after eating. Sugar and other nutrients are used to gain weight. energy in the body's cells and excessive production of liver sugar slows down. Own insulin is produced less, so more and more sugar in the blood and the level of blood sugar increases. In addition to genetic causes, the leading causes of type 2 diabetes are overweight and obesity. According to Deutscher Diabetes Hilfe, there are more than six million people with diabetes in Germany. The number of unreported cases is high – one in five does not know his illness.
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