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. 3 July 2018
People with migraine are at increased risk of developing cardiovascular disease. Epidemiologists have reached this conclusion in two large studies of the United States and Denmark. Particularly at risk are patients who experience an aura during their attacks.
People with migraine have an increased risk of vascular disease. "Two important recent studies from the United States and Denmark show that migraine sufferers are more likely to suffer heart attacks, strokes and venous thrombosis," said Privatdozent Dr. Med. med. Charly Gaul, General Secretary of the German Migraine and Headache Society (DMKG)
About one-fifth of all women and eight percent of men are affected by migraine, DGN and DMKG report in their medical guideline current, which appeared in late April. This makes migraine the most common neurological disease in Germany. Severe, often unilateral headaches badociated with loss of appetite, nausea, and vomiting are among the typical features of headache disorder. Although a large number of drugs are available for the treatment and prevention of migraine attacks, a significant proportion of migraine sufferers are not or insufficiently treated, as shown by a representative study of DMKG.
if people with migraine are more likely to be affected by cerebrovascular and cardiovascular events than others. Evidence has been used in recent years for several studies of selected populations, which are now confirmed by two large studies
Comparative Studies with 450,000 Patients
"Largest published meta-badysis of the badociation between cerebrovascular and cardiovascular diseases with migraine is based on data from 16 studies, "says DMKG Gaul's general secretary, with approximately 400,000 migraine patients and around 750,000 unaffected people included as controls. Vascular events increased the risk of migraine patients by 42%, stroke by 41% and heart attack by 23%
The risk was unequally distributed among different types of migraine: one-third of migraine patients. of an aura in their seizures – visual disturbances such as flickering lightning or loss of visual field – presented an increased risk of Stroke of 56% and while the death rate for diseases of all kinds in the entire group was not higher than for controls, this was not the case for migraines with aura. The total mortality of these patients has increased by 20%.
Similar results are reported in a study from Denmark comparing data from more than 50,000 patients in the country over a period of up to 19 years with those of 500,000 controls.
Avoidable Risk Factors
A group of patients requires special attention, as shown in the study data: "Women with frequent migraine attacks should be asked about their vascular risk factors and then treated consistently. Smoking and oral hormonal contraception are of particular importance. The question of whether effective treatment of migraine can reduce the risk of vascular events has not yet found an answer. "To prove it, studies with an observation period of more than ten years should be carried out," Gaul said.
"The mortality of migraine sufferers is not higher than in the general population.But doctors who treat migraine sufferers should be aware of the risk," says Professor Dr. med. Hans-Christoph Diener of the German Society of Neurology (DGN). He advises, especially to frequent migraine sufferers with aura on cardiovascular disease risk factors to examine and proactively treat them.
The text is based on a press release of the German Society of Neurology
German Society for Neurology eV
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