goChildren with severe eczema at a higher risk of food allergy



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In a new study published today in the Journal of Allergy and Clinical Immunology, scientists at King's College London found that young children with severe eczema infected with the bacteria Staphylococcus aureus ( SA) were at a higher risk of developing a food allergy.

Staphylococcus aureus (SA) is a bacterium found in the nose and skin of healthy individuals. However, AS is more common in people with eczema, especially severe eczema. When a person has an allergy, their immune system considers a harmless substance (such as eggs or peanuts) as an intruder and reacts excessively. Their body produces a molecule or an antibody called Immunoglobin E (IgE). When IgE encounters the intruder on the skin or in the body, it releases chemicals, such as histamine, that cause the allergic reaction.

The team of scientists discovered that young children with severe eczema and infected with AS were producing more IgE against peanuts, eggs and milk, indicating an allergy food to each of these.

The egg allergy of these children was also more likely to persist at the age of 5 or 6 years compared to children who did not have AS.

Dr. Olympia Tsilochristou, senior author at King's College London, said: "This is important because most children with egg allergies usually outgrow it earlier. We do not yet know the exact mechanisms that lead from eczema to food allergy. However, our results suggest that Staphylococcus aureus bacteria could be an important contributor to this outcome. "

These results are based on the precedents of the Learning Early About Peanut Allergy study (LEAP), which demonstrated that infants at high risk of developing peanut allergy but consuming a snack containing peanuts while on along the study were prevented from later developing peanut allergy.

In the present study, scientists found that children with AS on the skin and / or nose were more likely to develop peanut allergy although they were fed peanuts at an older age. early under the LEAP study protocol.

Source: King's College London

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