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(New York, NY – June 4, 2019) – A theory proposing the existence of a dynamic interface between the environment and human physiology throughout life has earned a renowned researcher Mount Sinai the prestigious Outstanding Investigator Award from the National Institute of Environmental Protection Institute. Health Sciences (NIEHS). Manish Arora, Ph.D., will receive a total of $ 8 million over eight years to carry out research on his theory, known as the biodynamic interface.
This prize is supported by the NIEHS under the program "RIVER" (RIVER) "revolutionize research in environmental health and visionary". The program recognizes outstanding researchers in the field of environmental health, offering up to $ 750,000 per year over the next eight years.
Dr. Arora and his team will use this award to combine theory with newly developed technology to develop predictive models that can prevent disease decades before clinical signs are apparent. Dr. Arora's team will study disorders such as autism, attention deficit / hyperactivity disorder, schizophrenia and amyotrophic lateral sclerosis (also referred to as ALS or Lou Gehrig's disease), which appear at different stages of life under the influence of the environment and genetics.
"I am grateful to the National Institute of Environmental Health Sciences for this award that will help unlock the environmental underpinnings of diseases with causes and treatments that remain largely unknown," said Dr. Arora, Professor Edith J Baerwald, Vice President, Department of Environmental Medicine and Public Health, Mount Sinai School of Medicine, Icahn. "Understanding the environmental factors of autism, schizophrenia and ALS could identify specific pathways related to the pathology of the disease and could lead to an early warning system for these disorders and disorders. Other neurodevelopmental disorders The earlier these diseases will be diagnosed or predicted, the therapies will benefit. "
The team that developed the Biodynamic Interface Theory includes Paul Curtin, PhD, and Christine Austin, PhD, adjunct professors of environmental medicine and public health at the Icahn School of Medicine; Austen Curtin, PhD, Data Analyst; Lisa Maroski, consultant specializing in language and philosophy; and Alessandro Giuliani, PhD, professor of environmental health at the University of Rome.
This award is one of six RIVER awards announced in June to innovative researchers in the field of environmental health sciences. The RIVER program is part of a continuing effort to support pioneering independent research programs, as opposed to research projects, which is generally the way NIEHS has funded research funds in the past.
"The program is designed to give researchers intellectual and administrative freedom, as well as sustained support for up to eight years, to push their research into new and important directions," said Jennifer Collins, coordinator of the RIVER program. "The RIVER program, now in its second year, is looking to fund community researchers from NIEHS grant recipients who have already shown a broad vision and have the potential to continue their hard-hitting research through of a research award that focuses on scientific flexibility and stability. "
Dr. Arora is known for his groundbreaking work on biomarkers using the human baby and permanent teeth to restore the moment of exposure to various harmful chemicals and essential nutrients, as well as the biological response to these environmental factors. Dr. Arora has developed a method of using teeth to reconstruct prenatal and early exposures to nutrients and toxicants in neurological children. Methods such as tooth badysis have provided the Mount Sinai Institute for Exposomic Research with a broad approach to observe multiple exposures and models at once. A member of the Mount Sinai Exposomic Research Institute, Dr. Arora examines early-life environmental exposures and their effects on health, disease, and development. The Exposomics research takes a systematic, large-scale approach to understanding how the environment affects health outcomes throughout life.
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The grant number for this award is R35ES030435.
About the Exposomic Research Institute
The Institute of Scientific Research at Mount Sinai School of Medicine Icahn is the first research institute in the world devoted to the intensive study of the exposome, or the totality of environmental influences on human health. The mission of the Institute is to understand how the complex combination of nutritional, chemical and social environments affects health, disease and development later in life and to translate these results into new prevention and treatment strategies. For more information, visit http: // icahn.
About the Mount Sinai Health System
The Mount Sinai Health System is the largest integrated distribution system in New York City. It includes eight hospitals, a leading medical school and a large network of outpatient practices in the greater New York area. Mount Sinai's vision is to provide the safest care, the highest quality, the greatest satisfaction, the best access and the best value of any health system in the country. The health system consists of approximately 7,480 primary and specialty care physicians; 11 outpatient surgery centers in joint venture; more than 410 outpatient practices in the five boroughs of New York, Westchester, Long Island and Florida; and 31 affiliated community health centers. The Icahn School of Medicine is one of three medical schools to have been distinguished by many indicators: ranked in the top 20 by "Best Medical Schools" of US News & World Report, aligned with the hospital "Honor Roll" by US News & World Report, N ° 12 in the country for the funding of the National Institutes of Health and among the top 10 most innovative research institutes according to the ranking of the journal Nature in its index of innovation of nature. This reflects a particular level of excellence in the areas of education, clinical practice and research. Mount Sinai Hospital is ranked 18th in US News & World Report's "Honor Roll" for the best US hospitals; It is one of the top 20 hospitals in the country in cardiology / cardiac surgery, gastroenterology / gastrointestinal surgery, geriatrics, nephrology and neurology / neurosurgery, and in the top 50 in six other specialties of the "Best" issue. hospitals "2018-2019. The Mount Sinai Kravis Children's Hospital is also ranked nationally in five out of ten pediatric specialties by the US News & World Report. The ophthalmic infirmary at Mount Sinai in New York is ranked 11th in the country for ophthalmology and 44th for the ear, nose and throat. Mount Sinai Beth Israel, Mount Sinai St. Luke, Mount Sinai West and South Nbadau Communities Hospital are clbadified by region.
For more information, visit http: // www.
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