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Good oral hygiene is part of being a polite man. We never think about it, it's just part of our daily lives.
However, new research from the University of Bergen is an important argument for brushing one's teeth. The study found a correlation between gum disease (gingivitis) and Alzheimer's disease.
The data is so solid that researchers have revealed that gum disease plays a key role in the development or otherwise of Alzheimer's disease. It is also the first time that DNA evidence is provided for this relationship.
"We have found evidence based on DNA that gingivitis-causing bacteria can pbad from the mouth to the brain," said researcher Piotr Mydel of the Broegelmanns research laboratory in the US Department of Clinical Sciences. University of Bergen (UiB).
It turns out that this annoying bacteria does not only affect bad breath. Instead, it produces a protein that destroys nerve cells in the brain.
Never the destruction of cells is a key component of memory loss and therefore of Alzheimer's disease. The researchers point out that it is not the bacteria alone that causes the degenerative disorder.
However, the presence of these bacteria not only increases the risk of developing the disease substantially, but also causes a faster progression of the disease.
Previous studies have already indicated that the bacteria that cause gingivitis can move from the mouth to the brain. They also discovered that once on site, the bacteria shed harmful enzymes that could destroy nerve cells in the brain.
For the first time in its history, Mydel has produced DNA evidence of this process. Mydel and his team examined 53 patients with Alzheimer's disease and discovered the harmful toxic enzyme in 96% of cases.
Work on a drug to block the enzymes
Mydel and his colleagues are working on a drug to counteract this dangerous process. "We have been successful in developing a drug that blocks the harmful enzymes of the bacteria, thus delaying the development of Alzheimer's, and we plan to test this drug later this year," said Mydel.
Fortunately, in the meantime, you can do something to combat gingivitis. "Brush your teeth and use floss," says Mydel.
It sounds so simple and yet, this daily routine has implications for life. The researcher added that if you suffer from gingivitis and have a history of Alzheimer's, you should go to the dentist more often to clean your teeth.
The study is published in the journal Progress of science.
We know that we will definitely take oral hygiene more seriously. And you?
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