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DALLAS – In an badysis of the national lung cancer screening test, adults claiming to smoke unfiltered cigarettes had a risk of all-cause mortality of 30% and were almost twice as likely to die from bad cancer. lung.
The data, presented at the international conference of the American Thoracic Society, also revealed that smokers of light or ultra-light cigarettes shared the same risks of all-cause mortality and lung cancer mortality that smokers of ordinary cigarettes. In addition, these smokers were less likely to quit.
"Since the late 1960s, tobacco manufacturers have significantly changed their efforts to reduce the" tar yield "of cigarettes, which has the effect of reducing the health risks of cigarettes. However, 80% of lung cancers are linked to smoking, and it remains the leading cause of cancer deaths in the United States ", Nina Thomas, MD, of the Department of Pulmonary Medicine and Critical Care Medical University of South Carolina, said Healio pneumology. "With lung cancer screening, we have been able to reduce lung cancer mortality by 20%. If we can succeed in helping participants quit and abstain for seven years, there will be an additional 20% reduction in mortality. "
For this secondary badysis of the National Pulmonary Testing, researchers badessed clinical outcomes, including lung cancer incidence, lung cancer mortality, all-cause mortality, and tobacco abstinence. and addiction. The researchers used Cox and proportional logistic models to define the effect of cigarette type on clinical outcomes. They also used the Fagerström test for nicotine addiction, the heaviness index of smoking and the delay scores before the first cigarette to highlight the effect of each type of cigarette.
"These data help us, in clinical practice, to better stratify our patients according to risk and to individualize smoking cessation counseling based on the type of cigarette they smoke," said Thomas.
According to data presented at the ATS international conference, adults who reported smoking unfiltered cigarettes were 40% more likely to develop lung cancer (HR = 1.37; P = .0051), twice as likely to die from lung cancer (HR = 1.96; P <0.0001) and 30% more likely to die from any cause (HR = 1.28; P = .0033). Those who smoke unfiltered cigarettes were also more heavily dependent on nicotine than those who smoke filtered cigarettes (OR = 1.32; P <0.01).
The researchers also badyzed the results in smokers of light and ultra-light cigarettes. They found that smokers of these types of cigarettes appeared to be less dependent on nicotine (OR = 0.76; P <0.0001), but there was no difference between the incidence of lung cancer, lung cancer mortality or all-cause mortality compared to ordinary cigarette smokers. In addition, those who reported smoking light or ultra-light cigarettes were less likely to quit than those who smoke regular or unfiltered cigarettes (OR = 0.82; P <0.0001), according to the results presented here.
"The results have been surprising, not only in terms of the number of more dangerous unfiltered cigarettes, but also in the fact that light and ultra-light cigarettes are just as harmful despite the way they have been marketed for many years. years, "said Thomas Healio pneumology.
Thomas and his colleagues reported no difference in clinical outcomes between menthol and smokeless cigarette smokers.
"The results have already changed my clinical practice in that I am now asking my patients what type of cigarette they smoke, why and about their addiction," Thomas said. "An easy way to badess addiction is to ask them," How long after you wake up do you smoke your first cigarette? "
In the future, research could focus on developing a personalized and patient-centered tobacco treatment intervention to individualize smoking cessation, Thomas said. It will also be important, in future trials, to evaluate the effect of different types of cigarettes on lung cancer outcomes in subsets of high-risk individuals, such as people of lower socio-economic status and low-income individuals. Black people because "some types of cigarettes have been selectively marketed". these groups in the past, "she said Healio pneumology. – by Scott Buzby
Reference:
Thomas N et al. Abstract 5894. Presented at: International Conference of the American Thoracic Society; May 17-22, 2019; Dallas.
Disclosure: Thomas does not report any relevant financial information.
DALLAS – In an badysis of the national lung cancer screening test, adults claiming to smoke unfiltered cigarettes had a risk of all-cause mortality of 30% and were almost twice as likely to die from bad cancer. lung.
The data, presented at the international conference of the American Thoracic Society, also revealed that smokers of light or ultra-light cigarettes shared the same risks of all-cause mortality and lung cancer mortality that smokers of ordinary cigarettes. In addition, these smokers were less likely to quit.
"Since the late 1960s, tobacco manufacturers have significantly changed their efforts to reduce the" tar yield "of cigarettes, which has the effect of reducing the health risks of cigarettes. However, 80% of lung cancers are linked to smoking, and it remains the leading cause of cancer deaths in the United States ", Nina Thomas, MD, of the Department of Pulmonary Medicine and Critical Care Medical University of South Carolina, said Healio pneumology. "With lung cancer screening, we have been able to reduce lung cancer mortality by 20%. If we can succeed in helping participants quit and abstain for seven years, there will be an additional 20% reduction in mortality. "
For this secondary badysis of the National Pulmonary Testing, researchers badessed clinical outcomes, including lung cancer incidence, lung cancer mortality, all-cause mortality, and tobacco abstinence. and addiction. The researchers used Cox and proportional logistic models to define the effect of cigarette type on clinical outcomes. They also used the Fagerström test for nicotine addiction, the heaviness index of smoking and the delay scores before the first cigarette to highlight the effect of each type of cigarette.
"These data help us, in clinical practice, to better stratify our patients according to risk and to individualize smoking cessation counseling based on the type of cigarette they smoke," said Thomas.
According to data presented at the ATS international conference, adults who reported smoking unfiltered cigarettes were 40% more likely to develop lung cancer (HR = 1.37; P = .0051), twice as likely to die from lung cancer (HR = 1.96; P <0.0001) and 30% more likely to die from any cause (HR = 1.28; P = .0033). Those who smoke unfiltered cigarettes were also more heavily dependent on nicotine than those who smoke filtered cigarettes (OR = 1.32; P <0.01).
The researchers also badyzed the results in smokers of light and ultra-light cigarettes. They found that smokers of these types of cigarettes appeared to be less dependent on nicotine (OR = 0.76; P <0.0001), but there was no difference between the incidence of lung cancer, lung cancer mortality or all-cause mortality compared to ordinary cigarette smokers. In addition, those who reported smoking light or ultra-light cigarettes were less likely to quit than those who smoke regular or unfiltered cigarettes (OR = 0.82; P <0.0001), according to the results presented here.
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"The results have been surprising, not only in terms of the number of more dangerous unfiltered cigarettes, but also in the fact that light and ultra-light cigarettes are just as harmful despite the way they have been marketed for many years. years, "said Thomas Healio pneumology.
Thomas and his colleagues reported no difference in clinical outcomes between menthol and smokeless cigarette smokers.
"The results have already changed my clinical practice in that I am now asking my patients what type of cigarette they smoke, why and about their addiction," Thomas said. "An easy way to badess addiction is to ask them," How long after you wake up do you smoke your first cigarette? "
In the future, research could focus on developing a personalized and patient-centered tobacco treatment intervention to individualize smoking cessation, Thomas said. It will also be important in future trials to evaluate the effect of different types of cigarettes on lung cancer outcomes in subsets of high-risk individuals, such as those with lower socio-economic status and blacks. because these groups in the past, "she said Healio pneumology. – by Scott Buzby
Reference:
Thomas N et al. Abstract 5894. Presented at: International Conference of the American Thoracic Society; May 17-22, 2019; Dallas.
Disclosure: Thomas does not report any relevant financial information.
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