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June 17, 2019 – 11:47 AMT
PanARMENIAN.Net – New research in mice reveals a "pathway to healthy aging", hitherto unknown. A protein circulating in the blood of young mice resulted in improved health and visible signs of rejuvenation when researchers administered it to aging mice, Medical News Today.
In addition to hair loss, wrinkles and reduced mobility, less visible underlying body changes also characterize the aging process.
One of these changes is the loss of a type of "fuel" that keeps the body healthy: the nicotinamide adenine dinucleotide (NAD).
NAD plays a key role in metabolism, DNA repair, aging and longevity in general. Over time, however, aging cells are increasingly struggling to produce energy, in general, and NAD, in particular.
But, in the process of producing energy, there is another essential player – an enzyme called eNAMPT. New research shows that taking eNAMPT in the blood of younger mice and giving it to older mice increases NAD levels and prevents aging.
The results appear in the journal Cell Metabolism. Dr. Shin-ichiro Imai, Ph.D., professor of developmental biology at the Faculty of Medicine at the University of Washington in St. Louis, is the lead author of the study.
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