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LONDON: High cholesterol in middle-aged people is associated with an increased risk of developing dementia and Alzheimer’s disease more than a decade later, according to research, foreign media reported.
The study involved 1.8 million adults over the age of 40 with a follow-up period of up to 23 years or until the diagnosis of dementia.
Of 953,635 people with increased low-density lipoprotein cholesterol levels, 2.3%, or 21,602, were diagnosed with the disease.
While high levels of total cholesterol were also associated with increased risk, this link was weaker, suggesting that it is largely due to LDL.
Study director Dr Nawab Qizilbash, OXON Epidemiology, said: “Long-term follow-up studies are needed to assess whether the benefits of LDL cholesterol-lowering interventions can reduce the risk of dementia or dementia. Alzheimer’s disease.”
The study, published in The Lancet Healthy Longevity, is considered the largest of its kind and provides the strongest evidence on the relationship between blood cholesterol and dementia and Alzheimer’s disease. It was led by the London School of Hygiene & Tropical Medicine with the University of Tsukuba, Japan, and OXON Epidemiology.
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