CDC grants $ 15.88 million to Wayne State University to study surveillance for viral infections



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The U.S. Centers for Disease Control and Prevention has awarded $ 15.88 million to the emergency medicine department at Wayne State University School of Medicine to be the epicenter of a nationwide study into viral infections in county emergency services.

The “Enhancing US Surveillance of Laboratory Confirmed SARS-CoV-2, Influenza, and Other Respiratory Viruses through a Network of Emergency Departments” project will continue for three years.

Jeffrey Kline, MD, professor and associate chair of research for the Department of Emergency Medicine, is the overall principal investigator for the project, which will span emergency departments in 21 states and the District of Columbia, and 100 hospitals for surveillance of viral infections. . Data will be obtained from electronic medical records of participating hospital systems. Each participating system will receive a portion of the $ 15.88 million and have a principal investigator on site.

The project will continue until August 2024. “If we are successful at the end of the third year, we hope that this will be repeated for years to come,” said Dr Kline.

The study is based on the Emergency Care COVID-19 Suspected Registry, or RECOVER, a large clinical registry of patients from 155 emergency departments in 27 states tested for SARS-CoV-2 from March to September 2020, which Dr Kline founded.

This study network will be called RECOVER-CDC.

Patients will be identified based on the reason or main complaint for their visit to the emergency department.

We will report data on patients who have major complaints suggestive of viral syndromes, including, but not limited to, cough, fever, muscle pain, sore throat, nasal congestion, and respiratory distress. We will then determine how many are tested for SARS-CoV-2, influenza, respiratory syncytial virus and other viruses as part of usual care and, most importantly, their vaccination status. We will then follow the patients to determine whether they are admitted to the hospital or not, and their results and diagnoses within 30 days. “

Dr Jeffrey Kline, MD, Professor and Research Associate Chair, Department of Emergency Medicine

The researchers aim to determine how often symptomatic patients are screened for viral infections, the results of these tests, the results and diagnoses of patients with known or suspected viral infections, and the associations between results and vaccination status.

“We will have a lot of other questions. For example, the association of viral infections with the diagnosis of blood clots is of key interest to my own research,” said Dr Kline.

The study team includes assistant vice president of research and professor of emergency medicine Phillip Levy, MD, as co-investigator; Professor of Emergency Medicine and Director of Biostatistics, Epidemiology, and Research Design Core Robert Welch, MD, for analysis oversight; and EBRD Core statistician Liying Zhang, Ph.D., with initial support from the Director of Grant Management, Department of Emergency Medicine Lynn Marie Mango, MPH

The assignment number for this Centers for Disease Control and Prevention contract is 75D30121C11813.

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