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Lupus is a systemic autoimmune disease that occurs when the body's immune system attacks its own tissues and organs. Vusi, 25, was born to Zuma's late wife, Kate Mantsho. He was the youngest of five children.
Makatini said an intimate memorial service, between close family and friends, for the young Zuma would take place on Thursday.
The funeral will be held on Saturday at 9 am at the Rhema Recreation Center in Randburg, after which he will be buried at West Park Cemetery.
Makatini says that the family gathered daily to pray.
"We continue to gather for support and prayers between 6pm and 7pm at our home in Forest Town," she said.
The Zuma family also expressed their gratitude for the messages of condolence and support since the death of Vusi on Sunday evening.
"The Zuma family would like to express their deep gratitude for the warm messages of support the nation has extended to them," they said.
Others have sent tributes and messages to the family, including former public protector Thuli Madonsela. , EFF leader Julius Malema and former Nelson Mandela badistant, Zelda la Grange.
The Mercury Function
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