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The photograph shows an enlarged view of human bone cancer cells, which stopped growing when a drug molecule, GO289, blocked their circadian rhythm. Credit: USC Michelson Center for Convergent Biosciences
"It could become an effective new weapon to kill cancer" are words we all want to hear.
And they can be attributed to Steve Kay, professor of neurology, biomedical engineering and biological sciences at USC Provost, about a new drug that could help prevent cancer. In research conducted by scientists at the USC Michelson Center for Convergent Biosciences and the Institute of Transformative Biomolecules at Nagoya University, scientists used our circadian rhythms to "slow down" the growth of cancer cells. Tests on "human kidney cancer cells and acute myeloid leukemia in mice" have shown that circadian clocks of cancer cells can be modified to kill them.
"In some cancers, the disease takes up the circadian clock mechanism and uses it for the nasty purpose of developing," explained Steve Kay. "With the GO289 molecule, we can interfere with these processes and prevent cancer from developing. This could become an effective new weapon that kills cancer. "
The research was published in the journal Progress of science.
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