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The composition of bacteria and other microbes in the intestine could be directly related to the risk of dementia, according to a preliminary study presented in Honolulu at the 2019 International Stroke Conference of the American Stroke Association, a first Global meeting of researchers and clinicians dedicated to the science and treatment of cerebrovascular disease.
Researchers studying the population of bacteria and microbes in the intestine, called the gut microbiota, have discovered that these "insects" have an impact on the risk of heart disease and more. Japanese researchers studied 128 stool samples from dementia patients (not suffering from dementia) and found differences in the components of the gut microbiota in patients with memory impairment, suggesting that the contents of the The intestine influences the risk of dementia, along with other risk factors.
The badysis revealed that faecal concentrations of ammonia, indole, skatole and phenol were higher in dementia patients than in those without dementia. But the rates of bacteroids – organisms that normally live in the intestines and may be beneficial – were lower in patients with dementia.
"Although it is an observational study and we have evaluated a small number of patients, the odds ratio is certainly high, suggesting that intestinal bacteria could constitute a target for the prevention of dementia, "said Naoki Saji, MD, PhD, author of the study and vice president. Director of the Center for Comprehensive Care and Memory Research, National Geriatrics and Gerontology Center, Japan.
The study was funded by the project of the National Center for Geriatrics and Gerontology and NARO, an institute for the advancement of biotechnology research with advanced technological orientation.
Source: American Heart Association
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