High levels of physical activity related to calcification of the coronary artery

(HealthDay) – High levels of physical activity correlate with coronary artery calcification (CAC), but are not linked to increased mortality, according to a study published online Jan. 30, 2006. JAMA Cardiology.

Laura F. DeFina, MD, of the Cooper Institute of Dallas, and colleagues evaluated data on generally healthy men without prevalent cardiovascular disease (CVD), to examine the correlation between levels of cardiovascular disease. 39, high physical activity, a PCA prevalence rate and a risk of subsequent mortality.

The researchers found that, compared with men who accumulated less physical activity, those with at least 3,000 Metabolic Task Equivalents (MET) – minutes / week (min / week) were more likely to have a prevalent CAC. at least 100 Agatston units (AU) (relative risk, 1.11, 95% confidence interval, 1.03 to 1.20). After an average follow-up of 10.4 years, there were 759 and 180 all-cause and CVD deaths, including 40 and 10, respectively, among those with a physical activity of at least 3000 MET / min / week. . The probability of death was significantly lower in men with a CAC below 100 AU and a physical activity of at least 3000 MET / min / week compared to those with less than 1500 MET / min / week ( risk: 0.52, 95% confidence interval). 0.29 to 0.91); in men with a CAC of at least 100 AU, there was no significant increase in mortality among men of at least 3,000 MET / min / week against less than 1500 MET / min / week (risk ratio, 0.77, 95% confidence interval, 0.52 to 1.15).

"Our findings should rebadure patients and their health care professionals that it appears that these very active people can continue their exercise programs safely," write the authors.

An author has revealed financial links with the pharmaceutical industry.

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