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February 08, 2019, 00:39Washington, February 8 (Prensa Latina) Based on the arched shell of the Leopard Turtle and its center of gravity, US researchers have created insulin pills that could be the end of subcutaneous injections in diabetic patients.
The main author of the study, Giovanni Traverso, explained that the moisture dissolves the simple part of the pill (formed of a sugar) and discovers a microscopic needle that digs and releases its contained in the wall of the stomach, somehow a sting.
The gastroenterologist stated that the device developed was able to self-orient within a few milliseconds, thus ensuring that the end of the injection immediately came into contact with the tissue.
Each capsule has the size of a pea and is loaded with a needle containing between 0.3 and 0.5 mm of insulin badociated with polyethylene oxide.
Other materials (stainless steel and biodegradable polymers) are similar to those of other devices already approved by the US Food and Drug Administration, experts said.
They also reported that after swallowing and losing its contents, it can be excreted without damage to the digestive system.
The fact that it acts in the stomach makes it spread faster in the body than a normal subcutaneous injection, but to be able to work, the patient must be fasting, they warn.
This technology is the most powerful described so far, because the oral administration of protein is a challenge on which the scientific community has been working for a century, badured Maria Jose Alonso, of the University of Santiago de Compostela, in Spain. .
For the moment, it has only been tested on animals such as rats and laboratory pigs, but the results have been satisfactory.
ef / mv / lrc
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