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EOne study found that xercise could protect against Alzheimer's by triggering a hormone that promotes regeneration of brain cells.
Scientists have known for some time that exercise reduces the risk of developing dementia, but they did not know if there was a direct link or if the sick people were simply unable to train.
A new series of studies has now shown that a hormone released during exercise, called irisine, is depleted in the brains of people with Alzheimer's disease and can protect animals from memory loss and brain damage. .
Mice that swam almost daily for five weeks did not exhibit memory impairment despite beta-amyloid infusions – the protein blocking brain cells involved in Alzheimer's disease.
This not only suggests that exercise actually protects against dementia, but also that a medicine mimicking irisin might be the solution to prevent the disease.
"I would certainly encourage everyone to exercise, to promote brain function and health in general," said Dr. Ottavio Arancio, professor of pathology and cell biology and medicine at Columbia University.
"But this is not possible for many people, especially those who suffer from age-related diseases such as heart disease, arthritis or dementia.
"For these people, there is a special need for drugs that mimic the effects of irisin, protect synapses and prevent cognitive decline."
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