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[..] to make Neoantigen peptides for the PANDA (personalized and adaptive) cancer vaccine program.
Vaccines that activate the immune system play a key role in the prevention and treatment of human diseases. The development of cancer vaccines, however, has been effective only in cancers of viral origin, such as cervical cancers caused by the human papillomavirus. It has long been known that T cells play an important role in the recognition and control of tumor cells (2001, Shankaran). Exploiting T cells to target and kill specific cancer cell types (ie, immunotherapy) has emerged at the forefront of new anti-cancer therapies. Traditional immunotherapy approaches involving the targeting of existing tumor epitopes have had limited success, mainly because of low T-cell avidity due to thymic selection and central tolerance. The limited success of traditional immunotherapies outside the types of cancer induced by the virus has created new opportunities for new therapies.
Peptide neo-antigen therapy constitutes a significant paradigm shift in the manufacture of GMP peptides due to the need for several unique sequences of target peptides and a synthesis, quality control and control of the peptide. 39, a quick release. With this in mind, CPC Scientific has launched its new PeptiVac neoantigen manufacturing platform:
- GMP installations designed for high throughput manufacturing
- Affordable price for small-scale GMP projects
- Fast manufacturing, quality control and release.
About CPC Scientific CPC Scientific is a world-renowned CDMO specializing in the production of synthetic peptides. We work directly with biotechnology and pharma leaders to help bring life-changing treatments and diagnoses to market. We have the world's largest GMP peptide facility, which has successfully undergone numerous FDA inspections and audits by global pharmaceutical companies. CPC Scientific has the ability to serve customers from the early stages of drug discovery to clinical trials to commercial manufacturing.
About the UNC Lineberger Cancer Center The UNC Lineberger Cancer Center, founded in 1975, is one of 40 cancer treatment centers designed by the National Cancer Institute (NCl) of the country. The center's mission is to reduce the number of cancers and cancers in North Carolina and the country through research, treatment, training and awareness.
Contact
Chris Gothard
Marketing Director
4087343800
[email protected]
Follow the full story here: https://przen.com/pr/33287543
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