Heart Study at Apple Demonstrates Portable Capability to Detect Atrial Fibrillation



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PALO ALTO, Calif .– (BUSINESS WIRE– Researchers at Stanford University School of Medicine today
presented the preliminary results of the Apple Heart study, an unprecedented study
virtual study with over 400,000 registered participants. Researchers
reported that portable technology can safely identify heart rate
irregularities that later tests confirmed to be auricular
fibrillation, a leading cause of stroke and hospitalization
United States.

The study was launched with the sponsorship of Apple, Inc., in November 2017
determine if a mobile app using heart rate data
sensor on the Apple Watch can identify atrial fibrillation. the
condition often remains hidden because many people do not know
symptoms.

The main conclusions of the study include:

  • Overall, only 0.5% of participants received an irregular heartbeat
    notifications, an important finding in view of the concerns relating to
    over-reporting.

  • Comparisons between the detection of irregular pulses on Apple Watch and
    Electrocardiography (ECG) simultaneous patch recordings showed the
    Pulse detection algorithm (indicating a positive reading of the tachogram)
    has a positive predictive value of 71%. Eighty-four percent of
    participants who received irregular pulse notifications were
    found to be in atrial fibrillation at the time of notification.

  • One-third (34%) of participants receiving irregular information
    pulse notifications and tracking using a one-week ECG patch
    later were found to have atrial fibrillation. Since auricular
    fibrillation is an intermittent disease, it is not surprising
    remain undetected during subsequent monitoring of the ECG patch.

  • Fifty-seven percent of those who received an irregular heartbeat
    requested notifications of medical care.

"The results of the Apple Heart study highlight the potential role that
innovative digital technology can play in the more predictive creation and
preventative health care, "said Lloyd Minor, MD, Dean of Stanford
Medicine School. "Atrial fibrillation is only the beginning because
The study opens the door to further research on wearable technologies and
how they could be used to prevent illness before it hits – a key goal
Precision health. "

For the study, each participant had to own an Apple Watch.
(series 1, 2 or 3) and an iPhone. The latest Apple Watch, which
ECG integrated, was not part of the study because it was published
after the launch of the study. The application Apple Heart Study intermittently
checked the heart rate sensor for irregular measurements
impulse. If an irregular pulse was detected, the participant received a
notification and was invited to plan a telemedicine consultation with
a doctor involved in the study through American Well. The participants were
then sent ambulatory ECG patches via BioTelemetry, which was recording
the electric rhythm of their hearts for a week.

Stanford's principal investigators were Mintu Turakhia, MD, badociate.
Professor of Cardiovascular Medicine, and Marco Perez, MD, Associate
professor of cardiovascular medicine, and the study chair was Kenneth
Mahaffey, MD, professor of cardiovascular medicine.

"The results of the study could help patients and clinicians
understand how devices like Apple Watch can play a role in detecting
such as atrial fibrillation, a deadly and often undiagnosed disease
disease, "said Turakhia. "The virtual design of this study also provides
a solid foundation on which future research can be conducted for
explore the implications of wearable technology for health. "

"The performance and accuracy observed in this study provide
important information that we seek to understand the potential impact of
portable technology on the health system, "said Perez. "Further research
help people make more informed decisions about health. "

Researchers at the Lankenau Heart Institute, Jefferson Medical
College, The School of Medicine at the University of Colorado, Cooper Medical
School of Rowan University, StopAfib.org, the American Foundation for
Women's Health and Duke University also contributed to the study.

The Apple Heart study was funded by Apple, Inc.

About atrial fibrillation

Every year in the United States, 130,000 atrial fibrillation
deaths and 750,000 hospitalizations, according to the centers for
Control and prevention of diseases. The CDC considers that the condition
affects between 2.7 million and 6.1 million people. In addition, another
700,000 people may have undiagnosed atrial fibrillation.

About Stanford Medicine

A leader in the biomedical revolution, Stanford Medicine has a long
leadership tradition in pioneering research, creative teaching
protocols and effective clinical therapies. Our proximity to the
the resources of the university – including business schools, right,
Humanities and sciences, and engineering – our homogeneous relationship
with our affiliated adult and child hospitals, and our ongoing service
badociations with Silicon Valley companies,
We are uniquely positioned to accelerate the pace of new knowledge.
translated into tangible health benefits.

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