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Ah, coffee! It is delicious, helps you wake up and studies have even shown that, with moderation, it has many health benefits. New research suggests adding to this list to inhibit the growth of drug-resistant prostate cancer.
SEE ALSO: THREE COFFEE CUPS PER DAY MAY RETAIN TYPE 2 DIABETES
Kahweol acetate and cafestol
Japanese scientists have discovered that two compounds found in coffee, kahweol acetate and cafestol, inhibit the growth of prostate cancer cells in mice. Both compounds are hydrocarbons, naturally occurring in Arabica coffee.
"We found that kahweol acetate and cafestol inhibited the growth of cancer cells in mice, but that the combination seemed to work synergistically, leading to significantly slower tumor growth than in non-mouse. After 11 days, the untreated tumor had increased by about 3 to one and a half times the initial volume (342%), whereas tumors in mice treated with both compounds had increased by a little more than 'one and a half times (167%) of the initial size,' said Dr. Hiroaki Iwamoto, director of the study, Department of Integrated Treatment of Cancer and Urology, School of Medical Sciences of the 39th University of Kanazawa, Japan.
However, Iwamoto also noted that the research was simply a pilot study requiring further investigation. As such, it can not necessarily be applied to humans. Still, the results are promising.
"What this shows is that these compounds seem to have an effect on drug-resistant prostate cancer cells under the right circumstances, and that they also need further investigation." We are currently thinking about how we could test these results in a larger sample, and then in humans, "Iwamoto added.
A coffee warning
The researchers also warned of an excessive increase in coffee consumption.
"These results are promising, but they should not encourage people to change their coffee consumption.Coffee can have both positive and negative effects (for example, it can increase hypertension), so we need find out more about the mechanisms that underlie these findings before you can think of clinical applications.However, if we can confirm these results, we could have candidates to treat drug-resistant prostate cancer, "said the Professor. Atsushi Mizokami, Department of Integrative Therapy of Cancer and Urology, Graduate School of Medical Sciences of Kanazawa University.
Nevertheless, if you like your morning beer, the news is good. It should be noted that kahweol acetate and cafestol can be removed when the coffee is filtered. Therefore, if you want to make the most of the benefits of an espresso.
The study is published in a peer-reviewed journal Prostate
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