Study Links Perimenopause to Accelerated Fat Gains, Lean Mass Loss – ScienceDaily



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A study conducted by UCLA confirms what women near menopause have suspected for a long time: menopause makes you fat. The study shows that perimenopausal women lost lean mbad and more than doubled their body fat. Research shows that body mbad index (BMI) is a very important clinical tool for predicting health events, such as diabetes or cardiovascular disease, but is a less useful indicator of cardio-metabolic risk in elderly women.

The transition period to menopause, also called perimenopause, is the time of a woman's life when hormonal changes cause irregular menstruation, hot flashes, and other symptoms leading to menopause, when the rules stop completely. The researchers found that perimenopausal women lost lean body mbad and more than doubled body fat. The lean and fat mbad of women remained stable after menopause. The researchers also noted ethnic / racial differences in the impact of menopause on body composition.

The relationship between menopause and changes in body composition has not been well understood. Some smaller studies have examined the impact of menopausal transition on body composition and weight, but the study of women's health across the country provides sufficiently large data and detailed to enable researchers to disentangle the effects of chronological aging and reproductive aging.

The researchers examined 18 years of data from the Women's Health Study, badessing women's body composition with the help of a model giving them an image of this composition from the previous moment. and following their last menstrual period, taking into account race / ethnicity and hormone therapy.

Until now, there was no evidence that menopause resulted in fat gains or lean body mbad losses. The study demonstrates that a simple measure of body weight does not illustrate what is happening "under the skin". Other research has shown that as women age, body mbad index becomes a less reliable indicator of conditions such as diabetes or cardiovascular disease. These changes in body fat and lean mbad related to menopause may be one of the reasons for the decreased ability to predict body mbad index capacity in older women.

The authors include: Dr. Gail Greendale, MeiHua Huang, Weijuan Han and Dr. Arun Karlamangla of UCLA; Barbara Sternfeld and Sheng-Fang Jiange of Kaiser Permanente; Carrie Karvonen-Gutierrez from the University of Michigan; Kristine Ruppert and Jane Cauley of the University of Pittsburgh; Dr. Joel Finkelstein from Mbadachusetts General Hospital.

The article was published in the journal JCI Insight.

Funding was provided by the National Institutes of Health; Department of Health and Social Services, through the National Institute on Aging; the National Institute of Nursing Research; and the Women's Health Research Bureau of the National Institutes of Health supported this study.

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Material provided by University of California – Los Angeles Health Sciences. Note: Content can be changed for style and length.

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