Research shows that diabetes treatment could prevent Alzheimer's disease

LOS ANGELES, March 25 (Xinhua) – A new study from the University of Southern California (USC) shows that progression of dementia and Alzheimer's characteristic trouble is much faster in people with Alzheimer's disease. untreated diabetes.

USC Dornsife psychologists have discovered that patients with untreated diabetes were developing signs of Alzheimer's disease 1.6 times faster than people without diabetes, announced Monday the publication of A press release from the university.

According to a study published in the journal Diabetes Care, patients taking drugs for type 2 diabetes could keep Alzheimer's disease at bay.

"Our findings underscore the importance of catching diabetes or other metabolic diseases in adults as early as possible," said Daniel A. Nation, a psychologist at the College of Humanities, Arts and Sciences. the USC Dornsife.

"Among people with diabetes, the difference in the rate of development of the signs of dementia and Alzheimer's is clearly related in one way or another to the fact that they take it or not drugs to treat it, "said Nation.

For this study, scientists compared the "pathology of tau", the progression of brain entanglements that characterize Alzheimer's disease.

According to the study, when entanglements combine with sticky beta-amyloid plaques – a toxic protein – they disrupt signals between brain cells, impairing memory and other functions.

USC researchers badyzed data collected by the Alzheimer's Disease Neuroimaging Initiative on 1,289 people aged 55 and over. Of 900 of these patients, 54 had type 2 diabetes but were untreated while 67 were on treatment.

The researchers compared the results of brain and cerebrospinal fluid tests that could indicate signs of amyloid plaques and brain entanglements among the different categories of diabetic patients.

"It's possible that drugs to treat diabetes will make a difference in the progression of brain degeneration," Nation said. "But it's unclear exactly how these drugs might slow down or prevent the onset of Alzheimer's disease, so we need to study this."

Scientists increasingly view Alzheimer's disease as the result of a cascade of multiple problems. Composition factors range from exposure to pollution and genetics to heart and metabolic diseases. Enditem

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