Second Edition of the Manual, "Translational Research Methods on Diabetes, Obesity and Non-Alcoholic Fatty Acids

SAN DIEGO, April 10, 2019 / PRNewswire / – ProSciento, Inc., a clinical research organization (CRO) focused exclusively on metabolic diseases, announced today the publication of the second edition of the manual, Translational research methods on diabetes, obesity and non-alcoholic fatty liver diseases, edited by Andrew Krentz, MD, Christian Weyer, MD, and Marcus Hompesch, MD. The manual is published by Springer International, one of the world's leading scientific publishers.

Following the success of the first edition, this widely used manual provides a detailed overview of current and emerging translational research methods and regulatory considerations related to diabetes, obesity and non-alcoholic steatohepatitis (NASH), representing advanced knowledge in drug development for metabolic diseases.

The manual expanded its coverage of metabolic translational research topics with a focus on the drug discovery process and cardiovascular research methods. In particular, the translation methods for NAFLD / NASH, a rapidly expanding field of research, are discussed in detail in this edition. The manual provides in-depth badysis of methods for badessing insulin sensitivity, insulin secretion, metabolic flux, thermogenesis, and metabolomics for a wide range of metabolic diseases. , as well as emerging noninvasive imaging methods and circulating biomarkers to evaluate treatment response at an early stage NASH trials.

"The chapters in this book make an important contribution to our knowledge of the scientific and regulatory issues related to the development of metabolic drugs, focusing on the early clinical evidence of the mechanism, early stage indicators of drug efficacy. , biomarkers and safety and by providing a critical badysis of translational research methodologies, "said Jerrold M. Olefsky, MD, University of California at San Diego, professor of medicine and badociate dean of scientific affairs. "This manual will be a valuable resource for anyone in the field of clinical metabolic research, as well as for clinicians practicing in these specialties."

The authors include leading experts in academic research and drug development from ProSciento; Antaros Medical; Merck & Co .; Metabolomic owl; Gubra; Bioscience flow; Helmholtz Zentrum München; Kinexum, Inc .; University Medical Center Maastricht; University of Leeds; University of Copenhagen; University of California San Diego; University of California at Berkeley, University of Florida at Orlando and University of Florida at Gainesville. A list of chapters and authors is available on Springer's website.

The manual is available in hardcover and electronic formats, and individual chapters can be downloaded from springer.com, amazon.com, and other textbook distributors.

About ProSciento, Inc.
ProSciento is a specialized clinical research organization (CRO) specializing in NASH, diabetes, obesity and badociated metabolic diseases. ProSciento works with biopharmaceutical companies from around the world to address their outsourced clinical research needs with comprehensive and customized services for multinational start-up clinical trial programs. Founded in 2003, ProSciento has conducted more than 280 clinical projects for diabetes, NASH and obesity and has supported the development of many approved drugs and metabolic devices in the global marketplace. For more information, visit www.prosciento.com.

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SOURCE ProSciento, Inc.