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TORONTO – Health Canada says prolonged use of a medication commonly prescribed for the treatment of high blood pressure may increase the risk of developing non-melanoma skin cancer.
Hydrochlorothiazide is a diuretic, or water pill, which is also prescribed to reduce water retention related to heart failure and certain kidney and liver problems.
A safety review conducted by Health Canada found that taking this medication can make the skin more sensitive to the sun's ultraviolet rays and tanning equipment.
The review of research data suggests that patients taking the drug for more than three years could have a risk at least four times higher for developing skin cancer other than melanoma.
However, Health Canada states that because of the limitations of studies, such as the lack of data on sun exposure and their severity, there is uncertainty about the results.
Even in this case, it is advisable for people taking hydrochlorothiazide to limit exposure to UV rays and to consult a doctor if they identify new skin lesions or mole changes.
According to the Federal Ministry, physicians should consider alternative medications for patients at high risk of non-melanoma skin cancer, including those with fair skin or a personal or family history of skin cancer.
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