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Cardiovascular disease is a general term for any condition affecting the heart and blood vessels. This is the main cause of heart attack and stroke.
Different studies have suggested that taking a regular low dose of aspirin could prevent heart attacks and strokes even in people without cardiovascular disease. Aspirin works by brightening the blood, so it is thought that it prevents the formation of a clot.
However, a new study from Imperial College London proves that aspirin provides only a small benefit to people without cardiovascular disease – and that this benefit accompanies them. An increased risk of severe internal bleeding.
Scientists badyzed 13 clinical trials – involving more than 164,000 participants – that evaluated the regular use of aspirin to prevent heart attacks or strokes in people without cardiovascular disease.
Dr. Sean Zheng, lead author of Imperial Oil, said, "Our study provides an up-to-date overview of the benefits and risks badociated with the use of aspirin in non-disease-prone individuals. cardiovascular system. A significant number of people in the world who have never suffered a heart attack or stroke take aspirin in the hope of preventing such events from occurring . Our study shows that the cardiovascular benefits of aspirin are modest and that the risk of serious bleeding increases accordingly. "
The study suggests that aspirin undoubtedly reduces the risk of cardiovascular events, but increases the risk of significant bleeding (absolute risk increase of 0.47%).
Dr. Zheng explained, "We found that for every 265 patients treated with aspirin for 5 years, a heart attack, stroke, or death from cardiovascular disease would be prevented. Moreover, out of 210 patients treated with aspirin during the same period, a serious hemorrhagic event would occur ".
"However, more data is needed, but based on the available evidence, aspirin should not be taken by people who do not have cardiovascular disease."
"Several guidelines continue to recommend the use of aspirin in the prevention of heart attacks and strokes in people considered high-risk or in people with diabetes. Our study shows that in these groups, cardiovascular benefits and risk of bleeding were matched without clear evidence of a net benefit. This suggests that the use of aspirin in patients without cardiovascular disease should not be routinely recommended. "
This latest discovery is published in the journal of the American Medical Association.
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