Bad sleep related to genetics: study



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The team discovered that an unusual variant of this gene had an impact not only on sleep duration, but also on sleep quality.

LONDON: Suffering from sleep disorders? Blame the genetics. A new study has revealed that many parts of our genetic code could be responsible for poor sleep.

Researchers from Mbadachusetts General Hospital (MGH) and Exeter University have identified up to 47 links between our genetic code and the quality and quantity of sleep.

Among the genomic regions discovered is a gene called PDE11A. The team discovered that an unusual variant of this gene had an impact not only on sleep duration, but also on sleep quality.

"This study identifies genetic variants affecting sleep patterns and will provide new insights into the molecular role of sleep in humans," said lead author Samuel Jones of the University. d & # 39; Exeter.

"Changes in the quality, quantity and timing of sleep are related to several human diseases such as diabetes and obesity, as well as psychiatric disorders.

The study, published in the journal Nature Communications, examined the data of 85,670 participants from UK Biobank and 5,819 people from three other studies, wearing wrist accelerometers, which continuously record levels of blood pressure. ;activity.

They discovered that, collectively, genetic regions related to sleep quality are also linked to the production of serotonin, a neurotransmitter badociated with feelings of happiness and well-being. Serotonin is known to play a key role in sleep cycles and is theorized to help promote deeper and more restful sleep.

They also found that restless legs syndrome is related to poorer sleep due to genetic variants badociated with sleep measurements derived from accelerometer data.

Indo-Asian Information Service

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