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Security forces clashed with protesters in Sudan's capital, Khartoum, as anti-government demonstrations took place across the country.
Riot police used tear gas to try to split large gatherings.
The coordinating group consisting of doctors, engineers and teachers coordinating the protests indicates that they were detained in at least 50 locations around Sudan.
They started last month on the economy, but are now focused on the removal of President Omar al-Bashir.
Journalist Zeinab Mohammed Salih told the BBC Thursday was the biggest day of live memory events.
Police reportedly used tear gas to control the crowd in several neighborhoods in Khartoum.
Since the protests began, officials said 26 people have died so far, but human rights groups say more than 40 people have been killed.
Doctors have increasingly targeted doctors because of their high social status as well as the active role that some have played in the organization of demonstrations.
Last week, state forces fired on a 16-year-old boy and a doctor taking part in demonstrations in the Burri district of the capital.
The doctor who died, Dr. Babiker Abdulhemeed, had "more than 14 live bullets in the body," said a member of the Sudan Doctors Union at the BBC.
Some foreign journalists have been prevented from reporting events in the country.
In recent days, a number of journalists working for Al Jazeera, the Turkish news agency Anadolu and the Saudi channel Al Arabiya TV have been denied accreditation.
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