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February 13, 2019, 11:56London, February 13 (Prensa Latina) Recent research by British scientists suggests that the badysis of blood levels of deoxyribonucleic acid (DNA) could improve the early detection of lung cancer, published Wednesday in the journal Disease Models and Mechanisms.
The researchers regularly performed CT scans to monitor the development of small, precancerous lung tumors in rodents.
The team found that mice with cancerous lung tumors had higher levels of circulating DNA than healthy animals, and that the levels of DNA released into the blood by cancer tumors correlated with the size of the cancer cells. tumors observed on the scanner.
After badyzing the circulating DNA to determine the presence of the precise KRAS mutation responsible for tumor development, the specialists discovered that, in the later stages of tumor development where the tumor was still precancerous, the KRAS mutation could still be detected in traffic. DNA
The lead author of the study, Miguel Martins, believes that similar studies should be conducted on mice with precancerous lesions in other tissues to determine if circulating DNA could to be used in the early detection of the disease in patients.
Lung cancer is the leading cause of death from this disease in the world, mainly because of the difficulty in detecting it at an early stage.
lrg / jha / lrc
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